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Acurx Pharmaceuticals (ACXP) investor relations material

Acurx Pharmaceuticals Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary12 Nov, 2025

Executive summary

  • Regained full compliance with NASDAQ listing requirements after a 1-for-20 reverse stock split and meeting equity thresholds.

  • Granted a new Australian patent for DNA polymerase IIIC inhibitors, expanding global IP protection for the ACX-375C program.

  • Increased authorized shares from 200 million to 250 million following stockholder approval.

  • Presented new data on ibezapolstat’s microbiome-sparing properties at IDWeek and published structural biology research in Nature Communications.

  • Focused on developing novel antibiotics targeting Gram-positive bacteria, with ibezapolstat advancing toward Phase 3 trials for C. difficile infections.

Financial highlights

  • Ended Q3 2025 with $5.9 million in cash, up from $3.7 million at year-end 2024.

  • Raised $1.7 million during the quarter via equity line of credit and $1.4 million post-quarter from warrant exercise.

  • Q3 2025 net loss was $2 million ($1.23 per diluted share), improved from $2.8 million ($3.45 per share) in Q3 2024.

  • Net loss for the nine months ended September 30, 2025 was $6.4 million ($5.01 per share), improved from $11.3 million ($14.23 per share) year-over-year.

  • Research and development expenses for Q3 2025 were $0.4 million, down from $1.2 million year-over-year due to lower manufacturing and consulting costs.

Outlook and guidance

  • Ibezapolstat is Phase 3 ready, with plans to begin international clinical trials next year, subject to financing.

  • Current cash is not sufficient to meet anticipated requirements for at least 12 months; additional financing will be needed.

  • Exploring public-private partnerships and alternative pathways for phase III trial funding.

  • Operating expenses expected to remain steady or decrease further due to ongoing cost-cutting measures.

  • Anticipates potential major partnership or development news by the next earnings call.

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Frequently asked questions

Acurx Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company focused on developing antibiotic treatments for bacterial infections. The company's research and development efforts are primarily centered on addressing antibiotic resistance, targeting bacterial pathogens that pose a significant threat to public health. Acurx utilizes a novel approach to inhibit bacterial DNA synthesis, working to combat infections that are increasingly resistant to traditional antibiotics. Its pipeline includes various antibiotic candidates aimed at providing new therapeutic options for patients. The company is headquartered in Staten Island, New York, and its shares are listed on the NASDAQ.

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