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Adlai Nortye (ANL) investor relations material
Adlai Nortye Corporate Presentation summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Corporate Presentation summary30 May, 2025
Pipeline and research overview
Advancing first-in-class and best-in-class preclinical assets, including AN8025 and AN9025, with IND filings expected in 2025.
Global R&D and clinical operations span the U.S. and China, supporting a robust oncology pipeline.
Pipeline includes multi-functional T cell/APC modulators, pan-RAS inhibitors, and oral PD-L1 inhibitors targeting advanced solid tumors.
Multiple assets are progressing through clinical and preclinical stages, with key data readouts and updates anticipated by year-end 2025.
AN8025: Multi-functional T cell/APC modulator
AN8025 targets PD-L1, Lag3v, and CD86v, activating APCs and reactivating T cells for anti-tumor immunity.
Demonstrates superior T-cell activation and tumor cell killing compared to existing checkpoint inhibitors.
Shows potent anti-tumor activity in vivo and favorable PK/safety in non-human primates.
IND filing expected mid-2025, with multiple registrational trials planned.
AN9025: Oral pan-RAS (ON) inhibitor
AN9025 exhibits strong, sustained binding to CypA and RAS (ON) proteins, outperforming RMC-6236 in potency and duration.
Achieves deeper tumor regression and more durable RAS pathway inhibition in preclinical models.
Demonstrates approximately 100-fold greater potency in RAS mutant cell lines versus RMC-6236.
IND filing targeted for 2H 2025.
Basis for AN9025's superior RAS inhibition
AN4005's differentiated market approach
AN8025's clinical advantages over IOs?
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Next Adlai Nortye earnings date
Q2 20257 Nov, 2025
Next Adlai Nortye earnings date
Q2 20257 Nov, 2025
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Frequently asked questions
Adlai Nortye Ltd. is a global clinical-stage biopharmaceutical company primarily engaged in developing innovative immuno-oncology medicines. The company's mission is to improve patient lives by discovering and developing differentiated innovative treatments for cancer. It has a strategic focus on oncology, with research and development and global clinical operation centers located in the United States and China. The company is headquartered in North Brunswick, New Jersey, and its shares are listed on the Nasdaq.
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