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Anteris Technologies
Anteris Technologies (AVR) investor relations material
Anteris Technologies TD Cowen 46th Annual Health Care Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.TD Cowen 46th Annual Health Care Conference summary2 Mar, 2026
Platform innovation and clinical results
Developed a biomimetic valve platform, DurAVR, designed to restore aortic valve function and healthy laminar flow, addressing limitations of existing TAVR devices.
Achieved consistently low mean gradients (5-10 mmHg) in 140 patients, including challenging anatomies and valve-in-valve cases.
Demonstrated unique benefits such as left ventricular remodeling and significant reduction in LV mass, indicating disease modification.
Showed superior outcomes in small annuli and valve-in-valve settings, with better-than-first-valve mean gradients.
Patient-prosthesis mismatch rate was only 3%, much lower than the typical 30% seen with other balloon-expandable devices.
Clinical trial strategy and milestones
Large early feasibility cohort (140 patients) de-risked pivotal study and provided robust long-term data, with some patients followed for over four years.
Ongoing and upcoming presentations at major conferences (CRT, New York Valves, TCT) will highlight flow, LV remodeling, and other clinical outcomes.
Cardiac MRI (2D/4D) is increasingly used to assess flow post-implant, with pivotal studies incorporating these imaging endpoints.
The pivotal PARADIGM IDE trial is a global, head-to-head study with 1,000+ patients, aiming for enrollment completion by Q1 2027 and potential approval in 2028.
Study includes all risk categories and valve-in-valve, with secondary endpoints on hemodynamic superiority, laminar flow, and LV remodeling.
Competitive landscape and strategic partnerships
Recent Medtronic investment reflects strong industry interest; no special rights granted, but potential for future co-development discussions.
Medtronic's Evolut platform faces challenges with higher re-intervention rates, especially in small annuli, enhancing DurAVR's market opportunity.
DurAVR's balloon-expandable delivery system was designed with extensive physician input and IP protection, offering ease of use and advanced features like commissural alignment.
High enthusiasm and demand from leading global investigator sites, with rapid trial enrollment anticipated.
Long-term follow-up data (up to 7.5 years) will be available by the time of potential approval, supporting robust safety and efficacy claims.
Evolut 7-year data impact on market strategy?
Communicate DurAVR's advanced clinical benefits?
PARADIGM trial design: Key for guideline change?
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Next Anteris Technologies earnings date
Barclays 28th Annual Global Healthcare Conference10 Mar, 2026
Anteris Technologies
Next Anteris Technologies earnings date
Barclays 28th Annual Global Healthcare Conference10 Mar, 2026
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Frequently asked questions
Anteris Technologies Ltd is an Australian-based medical technology company focused on developing innovative structural heart solutions. The company’s primary area of expertise lies in advanced transcatheter heart valve systems, designed to treat patients with severe aortic stenosis and other heart valve diseases. Anteris Technologies leverages proprietary technology in 3D single-piece valve design and specialized tissue treatments to improve durability and performance in minimally invasive heart procedures. The company is headquartered in Brisbane, Queensland, and its shares are listed on the ASX.
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