Arcus Biosciences
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Arcus Biosciences (RCUS) investor relations material

Arcus Biosciences Q3 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2026 earnings summary4 Nov, 2026

Executive summary

  • Late-stage oncology programs center on casdatifan in clear-cell renal cell carcinoma (ccRCC) and quemliclustat in first-line metastatic pancreatic cancer; the immunology pipeline is expanding.

  • October ARC-20 data supported casdatifan activity across ccRCC treatment lines, with no unexpected safety signals at the data cutoff.

  • The portfolio spans multiple treatment lines and combines wholly owned programs with regional rights and partnerships.

Financial highlights

  • Q3 revenue was $9M vs. $26M YoY; license and development services revenue was $8M vs. $20M, and other collaboration revenue was $1M vs. $6M.

  • Q3 R&D expense was $117M vs. $141M YoY, G&A was $23M vs. $27M, and total operating expenses were $140M vs. $168M.

  • Q3 net loss was $128M vs. $135M, and diluted loss per share was $1.00 vs. $1.27.

  • Nine-month revenue was $67M vs. $214M; net loss was $347M vs. $247M.

  • September 30 cash, cash equivalents and marketable securities were $694M; October’s offering generated $288M gross proceeds and $270M net proceeds.

Outlook and guidance

  • Cash and investments plus October offering proceeds are expected to fund planned operations into 2029; expected FY 2026 GAAP revenue is $70M–$75M.

  • PEAK-1, the Phase 3 casdatifan plus cabozantinib study in 2L ccRCC, is fully enrolled; PEAK-20 is expected to initiate in Q4 2026.

  • PRISM-1 completed enrollment; its Phase 3 interim analysis in 1L metastatic pancreatic cancer is expected in Q4 2026.

  • 2027 plans include more mature ARC-20 data and early data for casdatifan combinations with ivonescimab and tivozanib; PEAK-1 Phase 3 data and casdatifan plus tivozanib data are anticipated in 2028.

  • R&D expense is expected to remain relatively consistent near term as increased casdatifan and immunology investment offsets decreases in other programs.

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Jefferies Global Healthcare Conference16 Nov, 2026
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Frequently asked questions

Arcus Biosciences Inc (RCUS) is a clinical-stage biopharmaceutical company focused on the development of cancer immunotherapies. By leveraging underexploited biological opportunities, Arcus aims to create treatments that can significantly improve patient outcomes. The company's product pipeline features a range of candidates, including AB928, a dual antagonist for adenosine receptors A2aR and A2bR, in combination with an anti-PD-1 antibody (AB122) and chemotherapy for treating metastatic triple-negative breast cancer or ovarian cancer and advanced malignancies. The company is headquartered in Hayward, California, and its shares are listed on the NYSE.