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Arcus Biosciences (RCUS) investor relations material
Arcus Biosciences Q3 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Late-stage oncology programs center on casdatifan in clear-cell renal cell carcinoma (ccRCC) and quemliclustat in first-line metastatic pancreatic cancer; the immunology pipeline is expanding.
October ARC-20 data supported casdatifan activity across ccRCC treatment lines, with no unexpected safety signals at the data cutoff.
The portfolio spans multiple treatment lines and combines wholly owned programs with regional rights and partnerships.
Financial highlights
Q3 revenue was $9M vs. $26M YoY; license and development services revenue was $8M vs. $20M, and other collaboration revenue was $1M vs. $6M.
Q3 R&D expense was $117M vs. $141M YoY, G&A was $23M vs. $27M, and total operating expenses were $140M vs. $168M.
Q3 net loss was $128M vs. $135M, and diluted loss per share was $1.00 vs. $1.27.
Nine-month revenue was $67M vs. $214M; net loss was $347M vs. $247M.
September 30 cash, cash equivalents and marketable securities were $694M; October’s offering generated $288M gross proceeds and $270M net proceeds.
Outlook and guidance
Cash and investments plus October offering proceeds are expected to fund planned operations into 2029; expected FY 2026 GAAP revenue is $70M–$75M.
PEAK-1, the Phase 3 casdatifan plus cabozantinib study in 2L ccRCC, is fully enrolled; PEAK-20 is expected to initiate in Q4 2026.
PRISM-1 completed enrollment; its Phase 3 interim analysis in 1L metastatic pancreatic cancer is expected in Q4 2026.
2027 plans include more mature ARC-20 data and early data for casdatifan combinations with ivonescimab and tivozanib; PEAK-1 Phase 3 data and casdatifan plus tivozanib data are anticipated in 2028.
R&D expense is expected to remain relatively consistent near term as increased casdatifan and immunology investment offsets decreases in other programs.
- Casdatifan data and Phase 3 plans span RCC treatment lines.RCUS
Investor Day 2026 - Pivotal ARC-20 data and phase III trials aim to establish casdatifan as a market leader in RCC.RCUS
Morgan Stanley 24th Annual Global Healthcare Conference - Upcoming data for casdatifan may establish new benchmarks in kidney cancer treatment efficacy.RCUS
12th Annual Cantor Fitzgerald Global Healthcare Conference - Major October data update for casdatifan aims to boost confidence in pivotal renal cancer trials.RCUS
Citigroup’s Biopharma Back to School Summit 2026 - Casdatifan and quemliclustat lead a robust pipeline with strong late-stage data and major market potential.RCUS
Corporate presentation - Casdatifan advanced in RCC, new partnerships secured, and $775M cash runway projected into 2028.RCUS
Q2 2026 - Castatinopathy demonstrates superior efficacy in RCC trials, targeting major market growth.RCUS
H.C. Wainwright 27th Annual Global Investment Conference - Q1 2025 net loss was $112M on $28M revenue; cash reserves strong at $1B.RCUS
Q1 2025 - Casdatifan outperforms belzutifan in ccRCC, with strong efficacy, safety, and major market potential.RCUS
Status Update
Next Arcus Biosciences earnings date
Next Arcus Biosciences earnings date
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