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Astellas Pharma (4503) investor relations material

Astellas Pharma Q2 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2026 earnings summary30 Oct, 2025

Executive summary

  • Revenue and core operating profit saw significant year-on-year growth, driven by strong performance of strategic brands such as PADCEV, VYLOY, and others, as well as robust cost optimization initiatives.

  • Achieved exceptional Q2 YTD results, significantly outperforming expectations and prompting a major upward revision of full-year forecasts.

  • Pipeline progress included unprecedented PADCEV data, promising results for ASP3082 and ASP2138, and approvals for IZERVAY in Japan and Australia.

Financial highlights

  • Revenue reached ¥1,030.1 billion, up 10.1% year-on-year; underlying growth excluding forex impact was 12%.

  • Core operating profit rose to ¥282.6 billion, up 54.4% year-on-year; margin increased by 7.9 percentage points to 27.4%.

  • Operating profit was ¥199.4 billion, up 112.8% year-on-year; net profit doubled to ¥147.6 billion.

  • Free cash flow increased to ¥252.4 billion from ¥21.7 billion year-on-year.

Outlook and guidance

  • Full-year revenue forecast revised upward by ¥100 billion to ¥2,030 billion, surpassing ¥2 trillion for the first time.

  • Core operating profit forecast raised by ¥80 billion to ¥490 billion; core profit forecast increased to ¥365 billion.

  • Core operating profit margin expected at 24.1%, up 2.9 percentage points from initial forecast.

  • Continued strong growth expected for Strategic Brands in the second half.

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Frequently asked questions

Astellas Pharma Inc., is a Japanese multinational pharmaceutical company that emerged from the merger between Yamanouchi Pharmaceutical Co., Ltd. and Fujisawa Pharmaceutical Co., Ltd. in 2005. Astellas focuses on several key therapeutic areas including oncology, urology, immunology, cardiology, and infectious diseases, with a priority on research and development in infectious diseases, diabetes, gastrointestinal diseases, oncology, and central nervous system diseases. Astellas Pharma Inc. is headquartered in Tokyo, Japan, and its shares are listed on the Tokyo Stock Exchange.

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