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Edge14 Nov 2025
Ball: The King of Cans
From a 19th-century glass-jar legacy to a global plant network, Ball is now a pure-play aluminum can partner to the world's biggest beverage brands.
Atea Pharmaceuticals (AVIR) investor relations material
Atea Pharmaceuticals Status Update summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Status Update summary13 Nov, 2025
Clinical program and regimen profile
Phase III program compares a new regimen (bemnifosbuvir + ruzasvir) to the standard of care, aiming for a shorter, more convenient treatment with minimal drug-drug interactions.
Phase II results showed a 98% SVR12 rate, supporting advancement to phase III.
New data show no risk of drug-drug interactions with proton pump inhibitors, a key differentiator.
Bemnifosbuvir demonstrates a dual mechanism of action, inhibiting both viral replication and secretion.
The regimen is effective even in the presence of NS5A resistance and supports flexible dosing.
Phase III program status and design
Two pivotal trials (CBEYOND in North America, CFORG globally) will enroll about 1,760 patients.
CBEYOND enrollment is on track for completion next month, with top-line results expected mid-2026.
CFORG enrollment completion is expected mid-2026, with results by year-end 2026.
Both trials are open-label, randomized, and stratified by cirrhosis status and genotype, including HIV co-infected patients.
Primary endpoint is SVR12, the definitive measure of HCV cure.
Market opportunity and prescriber feedback
Market research among top US DAA prescribers shows 76% are extremely likely to prescribe the new regimen.
Prescribers would use the regimen in about half their patients, with similar results for non-cirrhotic and cirrhotic cases.
Consistent preference for the regimen has been shown in three separate studies over two years.
How BEM/RZR attributes expand treater base
Payer strategy for HCV elimination with BEM/RZR
BEM's dual mechanism impact on resistance
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Next Atea Pharmaceuticals earnings date
Q4 202527 Feb, 2026
Next Atea Pharmaceuticals earnings date
Q4 202527 Feb, 2026
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Frequently asked questions
Atea Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company focused on developing antiviral therapies for the treatment of viral diseases. The company's research and development efforts primarily target diseases such as hepatitis C, dengue, and COVID-19. Atea leverages its expertise in nucleoside and nucleotide therapeutics to create treatments aimed at addressing unmet medical needs in the antiviral space. The company is headquartered in Boston, Massachusetts, and its shares are listed on the NASDAQ.
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