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Athira Pharma (ATHA) investor relations material
Athira Pharma Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2025 earnings summary7 Aug, 2025
Executive summary
Focus shifted to ATH-1105 for ALS after pausing fosgonimeton development due to unsuccessful LIFT-AD trial results; strategic alternatives including partnerships or transactions are being explored.
Phase 1 trial for ATH-1105 completed in November 2024, showing favorable safety, tolerability, and pharmacokinetics in healthy volunteers; positive data presented in May 2025.
Company is actively reviewing options to maximize stockholder value, with Cantor Fitzgerald & Co. as advisor.
Financial highlights
Net loss for Q2 2025 was $7.0 million ($0.18 per share), a 74% improvement from $26.9 million ($0.70 per share) in Q2 2024.
Net loss for the six months ended June 30, 2025 was $16.1 million, down from $53.2 million for the same period in 2024.
Cash, cash equivalents, and investments totaled $29.8 million as of June 30, 2025, down from $51.3 million at year-end 2024.
Operating expenses for Q2 2025 were $7.3 million, down 74% year-over-year, driven by reduced R&D and G&A costs.
Net cash used in operations was $21.7 million for the first half of 2025, compared to $48.1 million in the prior year period.
Outlook and guidance
Existing cash and investments are expected to fund operations and capital expenditures through at least the next 12 months.
Additional capital will be required to advance ATH-1105 and other programs; options include equity, debt, or strategic transactions.
Plans to initiate a clinical trial of ATH-1105 in ALS patients, either independently or with a partner, pending strategic review.
Research and development and G&A expenses are expected to remain lower in the near term due to restructuring and program focus shift.
How do strategic alternatives impact ATH-1105?
Cash runway estimate based on current burn?
Any future for fosgonimeton despite trial results?
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Next Athira Pharma earnings date
Q3 20257 Nov, 2025
Next Athira Pharma earnings date
Q3 20257 Nov, 2025
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Frequently asked questions
Athira Pharma Inc., also known as Athira Pharma, is a late clinical-stage biopharmaceutical company focused on developing small molecules aimed at restoring neuronal health and slowing neurodegeneration. The company's leading product candidate, ATH-1017 (Fosgonimeton), is designed to enhance the activity of the hepatocyte growth factor (HGF) and its receptor, MET. The company is headquartered in Bothell, Washington, and its shares are listed on the NASDAQ.
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