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Autolus Therapeutics (AUTL) investor relations material
Autolus Therapeutics Q2 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Net product revenue for Q2 2026 reached $45.7 million, up 119% year-over-year and 74% sequentially from Q1 2026, driven by increased demand and expansion into new treatment centers in the US and UK.
Full-year 2026 net product revenue guidance for AUCATZYL raised to $140–$150 million, reflecting higher than expected sales momentum.
Gross margin improved to 55% in Q2 2026, up from 6% in Q1 2026 and negative in all quarters of 2025, driven by higher volumes and cost reductions.
Loss from operations narrowed to $43.8 million in Q2 2026 from $61.2 million in Q2 2025; net loss was $39.1 million, down from $47.9 million year-over-year.
Cash, cash equivalents, and marketable securities totaled $201.6 million at June 30, 2026, expected to fund operations into Q2 2028.
Financial highlights
Q2 2026 net product revenue: $45.7 million, up from $20.9 million in Q2 2025 and $26.2 million in Q1 2026.
Cost of sales decreased to $20.5 million in Q2 2026 from $24.4 million in Q2 2025; cost of sales as a percentage of revenue dropped from 117% to 45%.
R&D expenses were $27.9 million in Q2 2026 (flat vs. Q2 2025); SG&A expenses increased to $41.2 million, reflecting commercialization and restructuring costs.
Net loss for Q2 2026 was $39.1 million, improved from $47.9 million in Q2 2025.
Cash, cash equivalents, and marketable securities totaled $201.6 million as of June 30, 2026.
Outlook and guidance
FY 2026 net product revenue guidance for AUCATZYL increased to $140–$150 million from prior $120–$135 million.
Gross margin expected to improve further toward 65–70% for adult ALL over time.
Cash runway into Q2 2028, supported by $201.6 million in cash and up to $100 million from a new credit facility.
Multiple clinical data readouts expected in late 2026 through 2028, including pivotal studies in pediatric ALL, lupus nephritis, and progressive MS.
No EU product revenue anticipated in 2026 as commercial launch in Germany and other EU countries remains on hold.
- Obe-cel delivers durable remissions in adult ALL, with persistence driving long-term outcomes.AUTL
Status Update - AUCATZYL's U.S. launch exceeds expectations, with expansion into Europe and autoimmune indications advancing.AUTL
Goldman Sachs 46th Annual Global Healthcare Conference - Expanding CAR T-cell therapy demonstrates robust efficacy, safety, and broadening market reach.AUTL
H.C. Wainwright 4th Annual Cell Therapy Virtual Conference - Strong commercial growth and pipeline progress, with high remission rates and expanding indications.AUTL
46th Annual William Blair Growth Stock Conference - Lead CAR-T therapy sees robust growth, margin gains, and broadening clinical impact.AUTL
Jefferies Global Healthcare Conference 2026 - Strong revenue growth, clinical progress, and operational efficiency drive future value.AUTL
Corporate presentation - Q1 2026 revenue hit $26.2M, gross margin turned positive, and major cost-saving steps were taken.AUTL
Q1 2026 - Obe-cel advances in B-ALL and lupus nephritis, with pivotal trials and EU/UK reviews ahead.AUTL
Status Update - AUCATZYL's US launch drove $9M Q1 revenue, UK approval, and pivotal trials in LN and MS ahead.AUTL
Q1 2025
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