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Autolus Therapeutics (AUTL) investor relations material
Autolus Therapeutics Jefferies London Healthcare Conference 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Jefferies London Healthcare Conference 2025 summary18 Nov, 2025
Launch progress and operational highlights
Lead CAR-T therapy, Aucatzyl (OBE-cel), is now active in over 60 centers, with approvals in the U.S., U.K., and Europe.
End-to-end manufacturing and logistics infrastructure established, with robust transatlantic supply chain.
Achieved $51 million in sales in the first nine months, attaining market leadership in CAR-T for acute leukemia.
High manufacturing success rate and strong market access, with no patients turned down by insurers to date.
Focus on expanding market share within current indications and optimizing operational efficiency to reduce costs.
Clinical data and safety profile
FELIX study showed a 77% overall remission rate and a median duration of response of 42 months.
Low rates of high-grade cytokine release syndrome (2%) and neurological adverse events (7%).
Long-term survival plateau observed, indicating durable remissions.
Real-world data collection underway via the ROCCA Consortium, with initial results replicating clinical trial outcomes.
Expansion and pipeline development
Efforts underway to increase use among treating physicians and patient awareness to drive market penetration.
Investigating frontline use in acute leukemia to reduce reliance on prolonged chemotherapy.
Pediatric studies progressing, aiming for label expansion to include patients under 18, supported by RMAT designation.
Active pipeline in autoimmune diseases, including lupus nephritis (LUMINA study) and progressive multiple sclerosis (BOBCAT study).
AutoAid dual-targeting approach in light-chain amyloidosis also in development.
ROCA data insights on Ocatzel real-world use
Ocatzel's registrational path for lupus nephritis
Will Ocatzel sales fund new indication launches?
Partial view of Summaries dataset, powered by Quartr API
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Next Autolus Therapeutics earnings date
Q4 202512 Mar, 2026
Next Autolus Therapeutics earnings date
Q4 202512 Mar, 2026
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Frequently asked questions
Autolus Therapeutics plc is a clinical-stage biopharmaceutical company engaged in the development of advanced T-cell therapies for the treatment of cancer. The company leverages its proprietary technologies to engineer CAR T-cell therapies aimed at providing life-changing benefits to patients with various cancer types. Some of their key clinical-stage programs focus on therapies for conditions such as adult acute lymphoblastic leukemia and multiple myeloma. Autolus was founded in 2014, following innovative developments in cell programming technology at University College London. The company is headquartered in London, United Kingdom, and its shares are listed on the Nasdaq.
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