Logotype for Avalo Therapeutics Inc

Avalo Therapeutics (AVTX) investor relations material

Avalo Therapeutics Stifel Virtual Immunology and Inflammation Forum summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
Logotype for Avalo Therapeutics Inc
Stifel Virtual Immunology and Inflammation Forum summary15 Sep, 2025

Company overview and lead program

  • Developing AVTX-009, a high-affinity anti-IL-1β antibody, currently in Phase 2b for hidradenitis suppurativa (HS), with full enrollment expected by end of year and data anticipated mid-2026.

  • AVTX-009 targets IL-1β, a key driver of inflammation in HS, with higher affinity and specificity compared to competitors.

  • The drug is designed for better lesion penetration, longer half-life, and improved dosing frequency.

Scientific rationale and competitive landscape

  • IL-1β is identified as the main pathologic driver in HS, with IL-1α not elevated in lesions and not contributing to chronic inflammation.

  • Previous anti-IL-1α therapies showed no effect in HS, supporting the focus on IL-1β.

  • Lutacisumab data in severe HS patients validated the IL-1β mechanism, showing significant efficacy even in TNF inhibitor failures.

  • AVTX-009 aims for higher efficacy due to pure IL-1β targeting and higher affinity.

  • The market is shifting from TNF inhibitors to IL-17s, but there remains a need for alternative mechanisms due to limited response rates.

Clinical trial design and progress

  • Phase 2b trial includes three arms (two active, one placebo), 222+ patients, 16-week duration, and HiSCR75 as the primary endpoint.

  • Dosing regimens include monthly and biweekly options with loading doses, aiming for rapid therapeutic levels and patient-friendly administration.

  • Enrollment is highly competitive but progressing well, with 75% completed and full enrollment expected in the fall.

  • Comprehensive endpoints include skin pain, quality of life, and draining tunnel assessments.

  • Statistical analysis will use appropriate imputation methods, avoiding exclusion of patients for incidental antibiotic use.

Partial view of Summaries dataset, powered by Quartr API
Research faster. Power your platform.

Next Avalo Therapeutics earnings date

Logotype for Avalo Therapeutics Inc
Q3 20257 Nov, 2025
Your earnings 
season toolkit.
Download
Free on both iOS & Android.

Next Avalo Therapeutics earnings date

Logotype for Avalo Therapeutics Inc
Q3 20257 Nov, 2025

The essential earnings season companion

The #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.

Live calls and transcripts

Listen to earnings calls, CMDs, investor conferences, and more – with a podcast-like experience.

Find what you need faster

Search for any keyword across all transcripts simultaneously.

Easily store key findings

Capturing important takeaways is as simple as it gets. Even during your lunch run or commute.

Your watchlist. Your dashboard.

Follow the companies that matter to you. Get a personalized feed with real-time updates.

Be the first to know

Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned.

Consensus estimates

Access analyst consensus estimates, valuation multiples, and revenue segments splits.

All IR material in one place

The easiest way to stay updated during earnings season.

Global coverage

All events from public companies. Live and recorded.

Just click and listen

No webcast links. No manual registrations.

Research anytime, anywhere

Built for professionals. Loved by everyone. Try our free mobile app.

excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
App-store-avatar.png play-store-avatar.png
Leroy DaleyApp Store
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
play-store-avatar
Eferix Drawings Google Play
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
App-store-avatar.png play-store-avatar.png
anuj283App Store
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
App-store-avatar.png play-store-avatar.png
Leroy DaleyApp Store
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
play-store-avatar
Eferix Drawings Google Play
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
App-store-avatar.png play-store-avatar.png
anuj283App Store
I can't remember the last time an app had such a positive impact on my investment process.
x-avatar
@ankurshah47_ x.com
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
App-store-avatar.png play-store-avatar.png
Amina0781App Store
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
x-avatar
@theshortbearx.com
I can't remember the last time an app had such a positive impact on my investment process.
x-avatar
@ankurshah47_ x.com
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
App-store-avatar.png play-store-avatar.png
Amina0781App Store
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
x-avatar
@theshortbearx.com

Frequently asked questions

Avalo Therapeutics Inc. is a U.S.-based biotechnology company focused on the development of targeted therapies for immune-mediated diseases. The company specializes in discovering and advancing treatments for autoimmune and rare diseases by leveraging its expertise in immunology and precision medicine. Avalo Therapeutics Inc. conducts research across various stages of drug development, from early discovery to clinical trials. The company is headquartered in Rockville, Maryland, and its shares are listed on the NASDAQ.

Quartr provides global coverage of all investor relation material from public companies.

  • Mobile app: Research anytime, anywhere with the #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.

  • Desktop (Quartr Pro): The leading platform for qualitative research, used daily by top firms and financial institutions.

  • Quartr API: Build custom solutions powered by live earnings calls, live transcripts, filings and reports, slide presentations, and more.

Yes, the Quartr mobile app is free on both iOS and Android.

Yes. Quartr provides global, industry-leading live coverage of company events such as regular earnings calls, capital markets days, M&A announcements, and investor conferences. Live with zero delays. Just click and listen.

Yes, capturing important takeaways is as simple as it gets. Even during your lunch run or commute.

Yes. Follow the companies that matter to you. Get a personalized feed with real-time updates, a tailored earnings calendar, and instant alerts when earnings calls go live.

Yes. Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned, regardless of who's talking.

Explore our global coverage