Candel Therapeutics
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Candel Therapeutics (CADL) investor relations material

Candel Therapeutics Q3 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2026 earnings summary12 Nov, 2026

Executive summary

  • Phase 3 prostate trial met its primary DFS endpoint (HR 0.70, p=0.0155); updated data showed a 41% reduction in recurrence or prostate cancer-specific death risk at median 58-month follow-up.

  • Aglატimagene prostate BLA submission is planned for mid-2027, subject to ongoing FDA dialogue and assay refinement.

  • Three SITC posters highlighted aglatimagene immune biomarker findings and linoserpaturev survival data.

Financial highlights

  • Q3 2026 operating expenses were $23.0M vs. $13.2M YoY; net loss was $21.9M vs. $11.3M.

  • Q3 R&D was $15.6M vs. $8.5M, reflecting higher clinical, manufacturing and regulatory costs, headcount and stock compensation.

  • Q3 G&A was $7.4M vs. $4.7M, mainly due to higher employee-related and commercial-readiness costs.

  • 9M 2026 operating expenses were $66.0M vs. $32.5M; net loss was $69.6M vs. $8.7M.

  • 9M operating cash use was $58.3M; financing cash inflow was $142.6M, lifting cash, cash equivalents and restricted cash to $203.5M.

Outlook and guidance

  • Cash and cash equivalents of $203.1M at September 30, 2026, are expected to fund the current operating plan into Q2 2028.

  • R&D and G&A costs are expected to rise as clinical programs advance, manufacturing capabilities develop and commercial-readiness work continues.

  • Additional capital will be required for aglatimagene commercialization, the NSCLC Phase 3 trial and further linoserpaturev development; potential sources include equity, debt, collaborations or licensing.

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Jefferies Global Healthcare Conference18 Nov, 2026
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Frequently asked questions

Candel Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing viral immunotherapies for cancer treatment. The company’s approach involves using genetically modified viruses to induce immunogenic cell death in cancer cells, which unmask tumor antigens within an activated microenvironment. This process triggers a systemic and durable immune response against tumors, acting as an in situ vaccination. Candel’s therapies are designed to potentially improve survival rates and maintain the quality of life for patients across various stages of cancer. The company is headquartered in Needham, Massachusetts, and its shares are listed on NASDAQ.