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Chemomab Therapeutics (CCMB) investor relations material
Chemomab Therapeutics Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary21 Nov, 2025
Executive summary
Advanced preparations for nebokitug Phase 3 trial in primary sclerosing cholangitis (PSC) with regulatory alignment from FDA and EMA for a single registration trial using a composite clinical endpoint.
Positive feedback and support from the PSC community and key opinion leaders for the Phase 3 trial design, with strong interest in trial participation.
Presented new clinical data at AASLD 2025 showing nebokitug's favorable safety and consistent improvements in key biomarkers in PSC patients treated up to 48 weeks.
Multiple partnering options for supporting the Phase 3 program are advancing, with a cash runway expected through the end of Q4 2026.
Financial highlights
Cash, cash equivalents, and short-term bank deposits totaled $10.2 million as of September 30, 2025, up from $9.5 million at June 30, 2025, but down from $14.2 million at December 31, 2024.
R&D expenses were $1 million in Q3 2025, down from $2.8 million in Q3 2024, reflecting the end of Phase 2 SPRING trial activities.
G&A expenses remained stable at $0.9 million for Q3 2025, similar to Q3 2024.
Net loss was $1.7 million for Q3 2025, compared to $3.5 million in Q3 2024.
492,409,320 ordinary shares (6,155,117 ADSs) were issued and outstanding as of September 30, 2025.
Outlook and guidance
Cash resources are expected to fund operations through the end of Q4 2026.
Plans to launch the nebokitug Phase 3 trial as soon as feasible, pending financial resources.
Phase 3 funding strategy details
Future R&D spend post-Phase 2 completion?
How does regulatory alignment impact trial timeline?
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Next Chemomab Therapeutics earnings date
Q4 202527 Feb, 2026
Next Chemomab Therapeutics earnings date
Q4 202527 Feb, 2026
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Frequently asked questions
Chemomab Therapeutics Ltd is an Israel-based clinical-stage biotechnology company focused on the development of therapies for fibrotic and inflammatory diseases. The company’s lead drug candidate is based on targeting CCL24, a chemokine involved in fibrosis and inflammation. Chemomab's pipeline includes treatments for conditions such as primary sclerosing cholangitis (PSC) and systemic sclerosis. The company conducts preclinical and clinical studies and collaborates with research institutions to advance its drug development efforts. Chemomab Therapeutics Ltd is headquartered in Tel Aviv, Israel, and its shares are listed on the NASDAQ.
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