COMPASS Pathways
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COMPASS Pathways (CMPS) investor relations material

COMPASS Pathways KOL Event summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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KOL Event summary7 Jan, 2026

Introduction and agenda

  • Provided updates on COMP360 programs for PTSD and TRD, including pivotal trial designs, commercial readiness, and a fireside chat with Q&A.

  • Outlined agenda: clinical rationale, trial design, commercial preparedness, integration into care networks, and unmet needs in PTSD and TRD.

KOL background and credentials

  • Dr. Gary Small, Director of Behavioral Health Breakthrough Therapies at Hackensack Meridian Health, shared clinical insights.

  • Presenters included the CEO, CMO, Chief R&D Officer, Chief Patient Officer, Chief Commercial Officer, and external experts from academic and clinical backgrounds.

  • Dr. Geoffrey Grammer (Greenbrook), Myriam Barthes (Journey Clinical), and Dimitri Cavathas (HealthPort) discussed care delivery models.

Market insights and analysis

  • PTSD affects over 13 million adults in the U.S. annually, with a $230 billion economic burden and high comorbidity with TRD; current treatments are limited and often poorly tolerated.

  • TRD impacts about 4 million U.S. adults, with only 2 approved medicines, high personal and societal costs, longer depressive episodes, higher mortality, and greater work loss compared to MDD.

  • Existing TRD treatments like Spravato are effective but operationally burdensome and underutilized.

How do CPT codes support broad COMP360 access?
Rolling NDA submission: What are the next steps
How COMP360 addresses Spravato's low penetration
Key 005 Part B data for payer discussions?
Rationale for two-dose PTSD trial design?
Most critical barrier for rapid COMP360 scaling?
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Next COMPASS Pathways earnings date

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Q4 202526 Feb, 2026
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Q4 202526 Feb, 2026

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Frequently asked questions

COMPASS Pathways Plc is a mental health care company developing psychedelic-based therapies for the treatment of mental health disorders. The company focuses on clinical research and development of psilocybin-assisted therapies for conditions such as treatment-resistant depression. The company is headquartered in London, United Kingdom, and its shares are listed on the NASDAQ.

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