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Context Therapeutics (CNTX) investor relations material

Context Therapeutics Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary5 Nov, 2025

Executive summary

  • Clinical-stage biopharma focused on TCE bispecific antibodies for solid tumors, advancing CTIM-76, CT-95, and CT-202 product candidates.

  • First patients dosed in Phase 1 trials for CTIM-76 (Jan 2025) and CT-95 (Apr 2025); CT-202 regulatory filings expected in Q2 2026.

  • Net loss of $23.1 million for the nine months ended September 30, 2025; accumulated deficit of $117.9 million.

  • Cash and cash equivalents of $76.9 million as of September 30, 2025, expected to fund operations into 2027.

Financial highlights

  • Research and development expenses for the nine months ended September 30, 2025: $20.0 million, down 1% year-over-year.

  • General and administrative expenses: $5.9 million, up 8% year-over-year.

  • Interest income increased 21% to $2.7 million for the nine months ended September 30, 2025.

  • Net loss per share (basic and diluted) for the nine months ended September 30, 2025: $(0.24).

Outlook and guidance

  • Cash position expected to fund Phase 1a trials for CTIM-76 and CT-95, initiation of CT-202 trial, and operations into 2027.

  • Additional capital will be required to support ongoing development and commercialization efforts.

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Guggenheim Securities 2nd Annual Healthcare Innovation Conference10 Nov, 2025
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Frequently asked questions

Context Therapeutics Inc. is a clinical-stage biopharmaceutical company that focuses on developing therapies for solid tumors. The company's primary focus is on T cell-engaging bispecific antibodies, including its lead candidate, CTIM-76. This investigational therapy targets Claudin 6 (CLDN6), a protein expressed in various solid tumors such as ovarian, endometrial, and testicular cancers, while being minimally present in healthy tissues. Another key candidate in their pipeline is CT-95, a bispecific antibody targeting mesothelin, which is also aimed at treating solid tumors. Context Therapeutics is headquartered in Philadelphia, Pennsylvania, and its shares are listed on the NASDAQ.

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