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Curis (CRIS) investor relations material
Curis Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Progress in clinical studies for emavusertib in PCNSL, CLL, and AML, with ongoing enrollment and new data presentations scheduled at major oncology conferences.
Emavusertib granted orphan drug designation by FDA and EMA for PCNSL; protocol for Phase 2 CLL study filed, with first patient dosing expected late Q4 2025 or early Q1 2026.
Recently sold royalty interest in Erivedge and related assets for $2.5 million, extinguishing a significant liability and ending future royalty revenue.
Accumulated deficit reached $1.3 billion as of September 30, 2025, with continued operating losses and substantial doubt about the ability to continue as a going concern.
Completed registered direct offering and private placement, extending cash runway into 2026.
Financial highlights
Net loss for Q3 2025 was $7.7 million ($0.49/share), improved from $10.1 million ($1.70/share) in Q3 2024; net loss for the nine months ended September 30, 2025, was $26.9 million ($2.19/share), down from $33.8 million ($5.77/share) in 2024.
Revenues for Q3 2025 were $3.2 million, up from $2.9 million in Q3 2024, primarily from Erivedge royalties.
R&D expenses for Q3 2025 were $6.4 million, down from $9.7 million in Q3 2024; G&A expenses were $3.7 million, slightly down from $3.8 million.
Cash and cash equivalents stood at $9.1 million as of September 30, 2025, with 12.7 million shares outstanding.
Weighted average shares outstanding increased to 15.7 million in Q3 2025 from 5.9 million in Q3 2024.
Outlook and guidance
Existing cash and equivalents expected to fund operations into Q1 2026; additional capital required to fund operations beyond that period.
Focused on enrolling additional patients for TakeAim Lymphoma to support regulatory submissions.
First patient in CLL Phase 2 study expected to be dosed late Q4 2025 or early Q1 2026, with data anticipated at ASH 2026.
Plans to seek additional funding through equity, collaborations, or strategic transactions, but faces significant difficulty raising capital.
If unable to secure funding, may need to delay or eliminate R&D programs, consider asset sales, or seek bankruptcy protection.
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