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Curis (CRIS) investor relations material
Curis Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Achieved net income of $19.4 million in Q4 2025, reversing a net loss of $9.6 million in Q4 2024, driven by a $27.2 million non-cash gain from the sale of Erivedge royalties.
Full-year 2025 net loss narrowed to $7.6 million from $43.4 million in 2024, reflecting lower R&D and G&A expenses.
Advanced clinical programs for emavusertib in PCNSL, SCNSL, CLL, and AML, with promising early efficacy and MRD conversion data.
Financial highlights
Q4 2025 revenues were $1.1 million, down from $3.3 million in Q4 2024, due to the sale of Erivedge royalty rights.
Research and development expenses decreased to $5.8 million in Q4 2025 from $9.0 million in Q4 2024; full-year R&D was $28.3 million, down from $38.6 million.
General and administrative expenses fell to $2.9 million in Q4 2025 from $3.4 million in Q4 2024; full-year G&A was $14.0 million, down from $16.8 million.
Recognized a $27.2 million non-cash gain in Q4 2025 from the release of liability related to the sale of future royalties.
Cash and cash equivalents were $5.1 million as of December 31, 2025, with 12.9 million shares outstanding.
Outlook and guidance
Cash runway expected into the second half of 2027, assuming exercise of Series B warrants from the January 2026 PIPE financing.
Ongoing enrollment in TakeAim Lymphoma and CLL studies, with regulatory filings for accelerated approval in PCNSL targeted in the US and Europe.
- Shareholders to vote on share increase, PIPE-related issuances, and a new equity incentive plan.CRIS
Proxy Filing19 Feb 2026 - Registers 107.7M shares for resale by PIPE investors; no proceeds to company; clinical-stage biotech.CRIS
Registration Filing13 Feb 2026 - Shareholders to vote on major share increase, PIPE-related issuances, and a new incentive plan.CRIS
Proxy Filing9 Feb 2026 - Emavusertib gains EU ODD as Q2 net loss hits $11.8M; cash runway extends into Q1 2025.CRIS
Q2 20242 Feb 2026 - Emavusertib delivers strong early results in NHL and AML, with expansion into solid tumors underway.CRIS
H.C. Wainwright 26th Annual Global Investment Conference 202420 Jan 2026 - Promising IRAK4 inhibitor data in AML and NHL drive pivotal trial plans and partnership interest.CRIS
2024 Cantor Fitzgerald Global Healthcare Conference20 Jan 2026 - Q3 net loss narrowed, emavusertib data positive, but cash only funds operations into mid-2025.CRIS
Q3 202414 Jan 2026 - Emavusertib demonstrates superior efficacy and safety in PCNSL and AML, with broad expansion planned.CRIS
H.C. Wainwright 27th Annual Global Investment Conference27 Dec 2025 - Emavusertib advanced toward accelerated approval with strong data and extended cash runway, but funding risks remain.CRIS
Q4 202426 Dec 2025
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