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Curis (CRIS) investor relations material

Curis Q4 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q4 2025 earnings summary19 Mar, 2026

Executive summary

  • Achieved net income of $19.4 million in Q4 2025, reversing a net loss of $9.6 million in Q4 2024, driven by a $27.2 million non-cash gain from the sale of Erivedge royalties.

  • Full-year 2025 net loss narrowed to $7.6 million from $43.4 million in 2024, reflecting lower R&D and G&A expenses.

  • Advanced clinical programs for emavusertib in PCNSL, SCNSL, CLL, and AML, with promising early efficacy and MRD conversion data.

Financial highlights

  • Q4 2025 revenues were $1.1 million, down from $3.3 million in Q4 2024, due to the sale of Erivedge royalty rights.

  • Research and development expenses decreased to $5.8 million in Q4 2025 from $9.0 million in Q4 2024; full-year R&D was $28.3 million, down from $38.6 million.

  • General and administrative expenses fell to $2.9 million in Q4 2025 from $3.4 million in Q4 2024; full-year G&A was $14.0 million, down from $16.8 million.

  • Recognized a $27.2 million non-cash gain in Q4 2025 from the release of liability related to the sale of future royalties.

  • Cash and cash equivalents were $5.1 million as of December 31, 2025, with 12.9 million shares outstanding.

Outlook and guidance

  • Cash runway expected into the second half of 2027, assuming exercise of Series B warrants from the January 2026 PIPE financing.

  • Ongoing enrollment in TakeAim Lymphoma and CLL studies, with regulatory filings for accelerated approval in PCNSL targeted in the US and Europe.

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