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Dimerix (DXB) investor relations material
Dimerix Investor Presentation summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Investor Presentation summary2 Sep, 2025
Strategic focus and disease overview
Advancing therapies for inflammatory kidney diseases with unmet clinical needs, focusing on FSGS, a rare condition causing irreversible kidney damage and lacking approved treatments.
DMX-200 is the lead candidate, targeting inflammatory pathways in FSGS, and has orphan drug designation, offering regulatory and commercial advantages.
Clinical development and evidence
DMX-200 is in a global Phase 3 trial (ACTION3) with 286 patients, showing positive interim results in reducing proteinuria and favorable safety signals.
FDA and Project PARASOL have validated proteinuria and eGFR as surrogate endpoints for full approval, with potential for accelerated approval based on interim data.
Manufacturing is scaled for commercial supply, and four licensing deals have been executed after extensive due diligence.
Market opportunity and competitive landscape
FSGS has a global prevalence exceeding 200,000 cases, with significant growth potential as diagnosis rates rise.
No approved therapies exist for FSGS; DMX-200 is the only inflammatory modulator in late-stage development, with limited competition from other drug classes.
Rare kidney disease drugs command high prices, with US retail prices up to $600,000 per year, and DMX-200 benefits from orphan drug pricing protections.
When is accelerated approval decision expected?
DMX-200's unique MOA vs. competitors?
What is the value potential from unlicensed territories?
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Next Dimerix earnings date
Q1 202623 Nov, 2025
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Frequently asked questions
Dimerix Limited is an Australian biopharmaceutical company focused on developing new therapies for rare and progressive diseases, particularly kidney and inflammatory diseases. The company’s lead candidate targets chronic kidney diseases, including focal segmental glomerulosclerosis (FSGS) and diabetic kidney disease, using a proprietary drug discovery and development platform. Dimerix applies receptor-based science to create treatments that address unmet medical needs in complex diseases with few current therapeutic options. The company is involved in clinical trials to advance its drug candidates towards regulatory approval. The company is headquartered in Melbourne, Victoria, and its shares are listed on the ASX.
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