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Eledon Pharmaceuticals (ELDN) investor relations material
Eledon Pharmaceuticals Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Advanced tegoprubart as a next-generation immunosuppressive therapy, with over 100 patients treated across transplantation programs.
Achieved key milestones, including Orphan Drug designation for tegoprubart in liver transplantation and positive clinical data in kidney and islet cell transplantation.
Financial highlights
Research and development expenses for 2025 were $66.3 million, up from $52.0 million in 2024, driven by expanded clinical trials and manufacturing scale-up.
General and administrative expenses for 2025 were $17.0 million, down from $18.6 million in 2024, mainly due to lower stock-based compensation.
Net loss for 2025 was $45.6 million ($0.52 per share), compared to $36.2 million ($0.66 per share) in 2024; excluding non-cash warrant liability gains, net loss was $79.1 million in 2025 and $67.1 million in 2024.
Cash and cash equivalents plus short-term investments totaled $133.3 million at year-end 2025, down from $140.2 million at year-end 2024.
Outlook and guidance
Anticipates FDA guidance and initiation of Phase 3 trial for tegoprubart in kidney transplantation.
Plans to initiate additional islet and liver transplantation trials and report long-term data from ongoing studies.
- Tegoprubart advances with strong safety, phase 3 plans, and expanding transplant indications.ELDN
Leerink Global Healthcare Conference 202611 Mar 2026 - Promising transplant therapy advances to phase III, with expansion into islet and xenotransplant studies.ELDN
Guggenheim Securities Emerging Outlook: Biotech Summit 202612 Feb 2026 - Key phase 2 transplant data and strong financial runway position the program for major milestones.ELDN
Guggenheim Securities Inaugural Healthcare Innovation Conference14 Jan 2026 - Phase II kidney transplant data for tegoprubart expected Q4, aiming for superior efficacy and safety.ELDN
Guggenheim SMID Cap Biotech Conference29 Dec 2025 - Tegoprubart advances with strong transplant data, pivotal trials, and broad expansion plans in 2024.ELDN
Leerink’s Global Healthcare Conference 202518 Dec 2025 - Up to $250M in securities registered, including $75M ATM equity, to fund immunology pipeline and operations.ELDN
Registration Filing16 Dec 2025 - Tegoprubart matched tacrolimus in efficacy but showed a superior safety profile in kidney transplants.ELDN
Piper Sandler 37th Annual Healthcare Conference4 Dec 2025 - Annual meeting to vote on directors, share increase, officer exculpation, and auditor ratification.ELDN
Proxy Filing2 Dec 2025 - Annual meeting to vote on directors, share increase, officer exculpation, and auditor ratification.ELDN
Proxy Filing2 Dec 2025
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