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Erasca
Erasca (ERAS) investor relations material
Erasca Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q4 2025 earnings summary12 Mar, 2026
Executive summary
Early clinical activity observed for ERAS-0015, with ongoing responses in multiple RAS-mutant tumors and favorable safety and pharmacokinetics as of January 2026.
Phase 1 monotherapy data for ERAS-0015 expected in H1 2026 and for ERAS-4001 in H2 2026.
Expanded global rights for ERAS-0015 through a licensing agreement covering China, Hong Kong, and Macau.
Completed a $259 million upsized public offering in January 2026, strengthening the balance sheet.
Financial highlights
Cash, cash equivalents, and marketable securities were $341.8 million as of December 31, 2025, down from $440.5 million a year earlier.
Net loss for Q4 2025 was $29.1 million ($0.10 per share), compared to $32.2 million ($0.11 per share) in Q4 2024.
Full-year 2025 net loss was $124.5 million ($0.44 per share), improved from $161.7 million ($0.69 per share) in 2024.
R&D expenses for Q4 2025 were $23.2 million, down from $26.1 million in Q4 2024; full-year R&D expenses were $92.9 million, down from $115.4 million in 2024.
G&A expenses for Q4 2025 were $9.4 million, slightly down from $9.6 million in Q4 2024; full-year G&A expenses were $38.6 million, down from $41.7 million in 2024.
Outlook and guidance
Cash position, including proceeds from the January 2026 offering, expected to fund operations into H2 2028.
Phase 1 monotherapy data for ERAS-0015 (US and China) expected in H1 2026; ERAS-4001 data expected in H2 2026.
Expansion and combination cohorts for both programs planned for 2027.
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Latest events from Erasca
- Lead RAS-targeted therapies show strong early data, with major trial updates expected in 2024.ERAS
Oppenheimer 36th Annual Healthcare Life Sciences Conference26 Feb 2026 - Early clinical data show promising efficacy and safety for next-generation pan-RAS and pan-KRAS inhibitors.ERASGuggenheim Securities Emerging Outlook: Biotech Summit 202612 Feb 2026
- Advancing innovative RAS/MAPK-targeted therapies with strong financial backing and pivotal trials.ERAS2024 Cantor Fitzgerald Global Healthcare Conference3 Feb 2026
- Refocused RAS/MAPK pipeline, strong clinical progress, and cash runway support key milestones to 2027.ERASGoldman Sachs 45th Annual Global Healthcare Conference1 Feb 2026
- Advancing RAS-targeted therapies with pivotal trials and strong preclinical results.ERASJefferies 2024 Global Healthcare Conference1 Feb 2026
- Pipeline prioritizes RAS/MAPK assets, with key clinical milestones and strong financial runway ahead.ERASMorgan Stanley 22nd Annual Global Healthcare Conference22 Jan 2026
- Naporafenib plus trametinib achieves 40% response in NRAS-mutant melanoma; RAS franchise advances.ERASR&D Update18 Jan 2026
- RAS-targeted therapies advance with strong data and new assets nearing clinical entry.ERASGuggenheim Securities Inaugural Healthcare Innovation Conference14 Jan 2026
- Lead RAS-targeting programs show promising early efficacy and safety, with key data expected in 2024.ERAS44th Annual J.P. Morgan Healthcare Conference13 Jan 2026
Next Erasca earnings date
Q1 20268 May, 2026
Erasca
Next Erasca earnings date
Q1 20268 May, 2026
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