Erasca
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Erasca (ERAS) investor relations material

Erasca Q3 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2026 earnings summary12 Nov, 2026

Executive summary

  • Pipeline centers on ERAS-0015, a pan-RAS molecular glue, and ERAS-4001, a pan-KRAS inhibitor; ERAS-12 is being advanced toward a potential partnership. Naporafenib development ended.

  • Cash, cash equivalents, and marketable securities totaled $947.8M at September 30, 2026; resources are expected to fund planned operations and stated milestones for at least 12 months.

Financial highlights

  • Q3 2026 net loss was $51.3M vs. $30.6M in Q3 2025; loss per share was $0.15 vs. $0.11, basic and diluted.

  • Nine-month net loss was $278.9M vs. $95.5M; operating expenses were $295.1M vs. $108.3M, including a $150.0M Joyo-related IPR&D charge.

  • Q3 R&D expense was $47.2M vs. $22.5M and G&A was $12.3M vs. $10.1M; nine-month R&D was $110.4M vs. $69.6M.

  • Nine-month loss per share was $0.87 vs. $0.34.

Outlook and guidance

  • ERAS-0015 monotherapy expansion and combination dose-escalation data are expected in H1 2027; a potentially registration-enabling 2L+ NSCLC trial is expected to start in H1 2027.

  • ERAS-0015 Phase 3 trials are expected to start in 1L PDAC in 2027 and RAS-mutant NSCLC from H2 2027 to H1 2028.

  • ERAS-4001 preliminary Phase 1 safety, tolerability, PK, and initial efficacy data were expected in H2 2026; expansion and combination cohorts are planned for 2027.

  • Cash resources are expected to fund planned operations and stated clinical milestones for at least 12 months; no product revenue is expected for years, if ever.

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Jefferies Global Healthcare Conference18 Nov, 2026
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Frequently asked questions

Erasca Inc. is a clinical-stage precision oncology company with a focused mission to develop therapies aimed at eradicating cancer. The company specializes in targeting the RAS/MAPK pathway, one of the most frequently mutated signaling pathways in cancer, which affects millions of lives globally each year. Erasca's research involves a comprehensive strategy to shut down this pathway using a modality-agnostic approach, which includes small molecules, large molecules, and protein degraders. These are developed alone or in combination to treat various types of cancers driven by RAS/MAPK pathway alterations. The company is headquartered in San Diego, California, and its shares are listed on NASDAQ.