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Erasca (ERAS) investor relations material
Erasca Q3 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Pipeline centers on ERAS-0015, a pan-RAS molecular glue, and ERAS-4001, a pan-KRAS inhibitor; ERAS-12 is being advanced toward a potential partnership. Naporafenib development ended.
Cash, cash equivalents, and marketable securities totaled $947.8M at September 30, 2026; resources are expected to fund planned operations and stated milestones for at least 12 months.
Financial highlights
Q3 2026 net loss was $51.3M vs. $30.6M in Q3 2025; loss per share was $0.15 vs. $0.11, basic and diluted.
Nine-month net loss was $278.9M vs. $95.5M; operating expenses were $295.1M vs. $108.3M, including a $150.0M Joyo-related IPR&D charge.
Q3 R&D expense was $47.2M vs. $22.5M and G&A was $12.3M vs. $10.1M; nine-month R&D was $110.4M vs. $69.6M.
Nine-month loss per share was $0.87 vs. $0.34.
Outlook and guidance
ERAS-0015 monotherapy expansion and combination dose-escalation data are expected in H1 2027; a potentially registration-enabling 2L+ NSCLC trial is expected to start in H1 2027.
ERAS-0015 Phase 3 trials are expected to start in 1L PDAC in 2027 and RAS-mutant NSCLC from H2 2027 to H1 2028.
ERAS-4001 preliminary Phase 1 safety, tolerability, PK, and initial efficacy data were expected in H2 2026; expansion and combination cohorts are planned for 2027.
Cash resources are expected to fund planned operations and stated clinical milestones for at least 12 months; no product revenue is expected for years, if ever.
- ERAS-0015 advances toward pivotal trials as expanded data and combinations approach.ERAS
Stifel 2026 Healthcare Conference 2026 - ERAS-0015 advances toward pivotal trials, backed by expanded data plans and roughly $1 billion in cash.ERAS
3rd Annual Guggenheim Healthcare Innovation Conference - High response rates and strong safety drive global trials and strategic combinations.ERAS
Morgan Stanley 24th Annual Global Healthcare Conference - ERAS-0015 delivers strong efficacy and safety in RAS-mutant cancers, advancing toward pivotal trials.ERAS
Corporate presentation - Robust cash position and positive clinical data support pivotal trials and milestones in 2027.ERAS
Q2 2026 - Early clinical milestones, extended cash runway, and strong preclinical data drive optimism.ERAS
BofA Securities 2025 Healthcare Conference - ERAS-0015 shows high potency and safety at low doses, with broad development and combination plans.ERAS
Guggenheim Securities Emerging Outlook: Biotech Summit 2026 - Naporafenib plus trametinib shows strong efficacy in NRAS-mutant melanoma; RAS franchise advances to IND in 2025.ERAS
R&D Update - Promising RAS/MAPK-targeted therapies advance with strong data and key milestones ahead.ERAS
43rd Annual J.P. Morgan Healthcare Conference 2025
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