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Evommune (EVMN) investor relations material
Evommune Q3 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Pipeline includes EVO301 and EVO756 clinical programs, plus preclinical EVO646 and licensed EVO570; EVO756 development in CSU and AD was discontinued after Phase 2b trials missed primary endpoints, while migraine development continues.
EVO301 Phase 2a AD results showed a 55% EASI reduction at Week 12 versus 22% on placebo (p<0.01), with responses deepening during follow-up; treatment was well tolerated.
EVO570 licensing broadened the pipeline; several clinical and data milestones are planned for 2027.
Cash, cash equivalents and investments of $262.3M support anticipated runway into H2 2029.
Financial highlights
Q3 2026 revenue was $0 versus $10.0M in Q3 2025; 9M revenue was $0 versus $13.0M, all from prior-year Maruho license revenue.
Q3 operating expenses were $33.3M and net loss was $30.9M, versus $23.3M and $12.5M; 9M expenses were $92.2M and net loss was $84.8M.
Q3 R&D was $24.6M versus $19.6M; 9M R&D was $68.3M versus $53.6M. Q3 G&A was $8.8M versus $3.7M; 9M G&A was $23.9M versus $10.7M.
9M expense increases reflected discovery research, personnel, stock compensation and public-company costs.
Outlook and guidance
EVO756 migraine Phase 2b enrollment began in July 2026, with initial results expected in H2 2027; EVO301 UC Phase 2 is planned for Q1 2027, with data expected in 2028.
EVO301 global Phase 2b AD trial is expected to start in mid-2027; plans include three dose regimens versus placebo, 16 weeks of dosing and follow-up through Week 24.
EVO570 Phase 1 is expected in Q1 2027, with healthy-volunteer and biomarker data targeted for mid-2027; Phase 2 in rheumatoid arthritis is planned for 2H 2027.
EVO646 Phase 1 is planned for H1 2027, with healthy-volunteer and biomarker data expected in 2H 2027; EVO756 migraine top-line data are expected in H2 2027.
Current-plan cash runway is expected into H2 2029; a $5.0M Maruho milestone triggered by October completion of the EVO756 CSU study is expected to be recognized as Q4 2026 revenue.
- EVO301 advances after positive AD Phase 2a results, with four programs moving toward key trials.EVMN
Corporate presentation - 2027 brings key readouts across IL-18, TLR7/8, VAV1 and migraine programs.EVMN
Stifel 2026 Healthcare Conference 2026 - EVO570 advances toward RA phase II, with phase I data expected mid-2027.EVMN
Investor update - Three immunology programs advance toward key clinical milestones through 2027–2028.EVMN
Corporate presentation - EVO570 pairs potent VAV1 degradation with a planned 2027 RA proof-of-concept path.EVMN
Company presentation - Advancing IL-18 and MRGPRX2 programs with strong funding and AI-driven innovation.EVMN
Morgan Stanley 24th Annual Global Healthcare Conference - Innovative therapies for inflammation, migraine, and autoimmunity advance toward late-stage trials.EVMN
Corporate presentation - Advancing two novel anti-inflammatory therapies with strong clinical and financial momentum.EVMN
Corporate presentation - Net loss rose to $53.9 million as expenses increased, but cash runway extends through 2028.EVMN
Q2 2026
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