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Investor Relations14 Oct 2025
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Fennec Pharmaceuticals (FENC) investor relations material
Fennec Pharmaceuticals H.C. Wainwright 27th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H.C. Wainwright 27th Annual Global Investment Conference summary9 Sep, 2025
Key business updates
Achieved three consecutive quarters of revenue growth, with Q2 net product sales up 33% year over year, reaching nearly $10 million.
Rebuilt commercial and medical organization, bringing in new leadership to expand market presence, especially in adolescent and young adult (AYA) segments.
Secured a global partnership with Norgine for commercialization in Europe, Australia, and New Zealand, with $43 million upfront and over $200 million in potential milestones.
PEDMARQSI launched in the UK and Germany, with further EU rollouts planned in the next year.
Japanese clinical trial results expected by year-end, targeting a market about one-third the size of Europe or the U.S.
Product and market insights
PEDMARK is the first and only FDA-approved agent to prevent cisplatin-induced hearing loss, showing about 50% reduction in hearing loss in phase III trials.
Holds strong IP protection: six U.S. Orange Book patents, seven years of U.S. exclusivity, and 10 years in Europe.
U.S. approval covers patients over one month old with localized, non-metastatic solid tumors; EU and UK approvals received in 2023.
NCCN Clinical Practice Guidelines now include a 2A endorsement for AYA patients, expanding the addressable market.
Pediatric market is highly concentrated, while the AYA market is larger and more dispersed across community centers.
Commercial execution and patient support
Organization now has 38 employees, with over half in customer-facing roles, and a new cross-functional leadership team.
Achieved over 80% reimbursement success with major insurers, supporting broad patient access.
Built strong relationships with key opinion leaders and audiologists to drive awareness and adoption.
Fennec HEARS program provides education, financial, and patient support, especially as focus expands to AYA patients.
Rebuilt support programs to ensure successful administration and reimbursement for both pediatric and AYA markets.
When do Norgine milestones begin to impact cash?
AYA market strategy for dispersed community centers
What drives H2 OpEx reduction to $15M?
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Next Fennec Pharmaceuticals earnings date
Q3 20256 Nov, 2025
Next Fennec Pharmaceuticals earnings date
Q3 20256 Nov, 2025
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Eferix Drawings Google Play
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Frequently asked questions
Fennec Pharmaceuticals Inc. is a specialized biopharmaceutical company primarily focused on developing treatments aimed at preventing ototoxicity (hearing loss) caused by platinum-based chemotherapy in pediatric cancer patients. Its flagship product, PEDMARK, represents a formulation of sodium thiosulfate designed to mitigate this side effect, catering to a niche yet critical aspect of pediatric oncology care. The company is headquartered in Research Triangle Park, North Carolina, and its shares are listed on the Nasdaq.
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