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Gossamer Bio (GOSS) investor relations material

Gossamer Bio Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary5 Nov, 2025

Executive summary

  • Focused on late-stage development and commercialization of seralutinib for pulmonary hypertension, with ongoing Phase 3 trials in PAH and PH-ILD, and a strategic global partnership with Chiesi for development and commercialization.

  • Completed enrollment of 390 patients in the Phase 3 PROSERA study for pulmonary arterial hypertension; topline results expected February 2026.

  • Activated first clinical site for Phase 3 SERANATA Study in PH-ILD in October 2025; enrollment to begin in Q4 2025.

  • Entered strategic agreements, including a global collaboration with Chiesi and an option to acquire Respira Therapeutics and its inhaled vardenafil candidate.

Financial highlights

  • Revenue for Q3 2025 was $13.3M, up from $9.5M in Q3 2024, driven by Chiesi collaboration cost-sharing.

  • Net loss for Q3 2025 was $48.2M ($0.21 per share), compared to $30.8M ($0.14 per share) in Q3 2024; nine-month net loss was $123.1M.

  • Cash, cash equivalents, and marketable securities totaled $180.2M as of September 30, 2025.

  • R&D expenses for Q3 2025: $45.5M; for nine months: $125.2M.

  • Working capital was $141.9M and total stockholders' equity was $(82.3)M as of September 30, 2025.

Outlook and guidance

  • Existing cash and equivalents expected to fund operations for at least the next 12 months, with some projections extending into 2027.

  • Topline data from the PROSERA Phase 3 study anticipated in February 2026.

  • No further clinical trials for inhaled vardenafil anticipated until at least 2027 if Respira option is exercised.

  • Ongoing need for additional capital anticipated as development and commercialization efforts continue.

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Frequently asked questions

Gossamer Bio, Inc. is a U.S.-based biopharmaceutical company focused on the discovery, development, and commercialization of innovative therapeutics in immunology, inflammation, and oncology. The company’s research pipeline targets diseases with unmet medical needs, including autoimmune disorders, inflammatory conditions, and cancer. Gossamer Bio leverages its scientific expertise to advance novel drug candidates through clinical trials, aiming to deliver effective treatment options for complex and chronic illnesses. The company is headquartered in San Diego, California, and its shares are listed on the NASDAQ.

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