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Gossamer Bio (GOSS) investor relations material
Gossamer Bio Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Focus shifted to evaluating PROSERA Phase 3 topline results, engaging with the FDA, and reassessing strategic options and capital allocation.
Enrollment in the Phase 3 SERANATA Study in PH-ILD paused pending review of PROSERA implications.
Workforce reduction and cost-containment measures implemented to align with near-term priorities.
Financial highlights
Cash, cash equivalents, and marketable securities totaled $136.9 million at year-end 2025, expected to fund operations into Q1 2027.
Q4 2025 R&D expenses were $48.9 million, up from $36.1 million in Q4 2024; full-year R&D expenses rose to $174.1 million from $138.5 million.
Q4 2025 G&A expenses were $10.9 million, up from $9.4 million in Q4 2024; full-year G&A expenses were $37.6 million, up from $36.1 million.
Q4 2025 net loss was $47.2 million ($0.21/share) vs. $33.0 million ($0.15/share) in Q4 2024; full-year net loss was $170.4 million ($0.75/share) vs. $56.5 million ($0.25/share) in 2024.
Total revenue for 2025 was $48.5 million, down from $114.7 million in 2024.
Outlook and guidance
Additional analyses of the PROSERA dataset ongoing; Type C FDA meeting planned for June 2026 to discuss regulatory paths.
Current cash position expected to fund operations into the first quarter of 2027.
- Seralutinib improved exercise capacity and biomarkers in high-risk PAH, with manageable safety.GOSS
Study result23 Feb 2026 - Seralutinib advances in global phase III trials, with Chiesi partnership accelerating PH-ILD expansion.GOSS
Presents at Goldman Sachs 45th Annual Global Healthcare Conference3 Feb 2026 - Seralutinib's phase III trials progress with strong data, global reach, and robust financial backing.GOSS
Guggenheim Securities Inaugural Healthcare Innovation Conference15 Jan 2026 - PROSERA nears enrollment completion, with Q4 data and commercial launch plans progressing.GOSS
Piper Sandler 36th Annual Healthcare Conference12 Jan 2026 - Seralutinib targets late-stage PAH and PH-ILD markets with best-in-class safety and strong commercial prospects.GOSS
Barclays 27th Annual Global Healthcare Conference 202526 Dec 2025 - Seralutinib advances in phase III with best-in-class safety, efficacy, and global reach.GOSS
Leerink’s Global Healthcare Conference 202526 Dec 2025 - Seralutinib’s phase III data in PH, expected late 2024, could reshape the treatment landscape.GOSS
Emerging Growth Conference 7923 Dec 2025 - Shareholders will vote on director elections, auditor ratification, executive pay, and equity plan changes.GOSS
Proxy Filing2 Dec 2025 - Virtual annual meeting to vote on directors, auditor, pay, and incentive plan approval.GOSS
Proxy Filing2 Dec 2025
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