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Heron Therapeutics (HRTX) investor relations material
Heron Therapeutics Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2025 earnings summary8 Aug, 2025
Executive summary
Q2 2025 net revenue reached $37.2M, with YTD revenue at $76.1M and strong operational milestones including a permanent J code for ZYNRELEF effective October 1, 2025.
Acute Care franchise revenue grew 55.5% year-over-year in Q2 2025, with ZYNRELEF and APONVIE unit demand up 6.3% and 19% sequentially.
Oncology segment revenue declined due to increased competition from generics and branded alternatives.
Completed comprehensive refinancing, reducing total debt from $175M to $145M and extending maturities to at least 2030.
Commercial restructuring and targeted sales initiatives implemented to drive future growth.
Financial highlights
Q2 2025 net revenues: $37.2M; first half 2025 net revenues: $76.1M.
Adjusted EBITDA for first half 2025: $7.9M; Q2 2025 adjusted EBITDA: $1.8M vs. $(1.2)M in Q2 2024.
Q2 product gross profit: $27.3M (73.5% margin), up from 70.8% in Q2 2024.
Q2 net loss: $2.4M vs. $9.2M loss in Q2 2024; first half 2025 net income: $0.3M vs. $12.4M loss in 2024.
Cash and short-term investments at June 30, 2025: $40.6M.
Outlook and guidance
2025 net revenue guidance maintained at $153M–$163M.
Adjusted EBITDA guidance raised to $9M–$13M from prior $4M–$12M.
Management expects continued acute care growth, while oncology faces ongoing competitive pressure.
Available cash and investments expected to cover needs for at least one year from the report date.
Net cash added from financing, excluding tranches?
ZYNRELEF J-code & NOPAIN Act adoption impact?
Rationale for ZYNRELEF/APONVIE sales force split?
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Next Heron Therapeutics earnings date
Q3 20254 Nov, 2025
Next Heron Therapeutics earnings date
Q3 20254 Nov, 2025
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Frequently asked questions
Heron Therapeutics Inc. is a biotechnology company focused on developing and commercializing therapies to address unmet medical needs in acute care and oncology. The company specializes in creating treatments for pain management and chemotherapy-induced side effects, such as nausea and vomiting. Heron Therapeutics utilizes its proprietary technology platforms to develop extended-release therapies that aim to improve patient comfort and treatment outcomes. The company is headquartered in San Diego, California, and its shares are listed on the NASDAQ.
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