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Inhibikase Therapeutics (IKT) investor relations material

Inhibikase Therapeutics Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary14 Nov, 2025

Executive summary

  • Advanced IKT-001, a prodrug of imatinib, toward a Phase 2b trial for pulmonary arterial hypertension (PAH) set to begin in Q4 2025; Parkinson's program discontinued and outlicensed.

  • Completed CorHepta Pharmaceuticals acquisition, resulting in a $7.4M non-cash R&D charge and $1.8M in stock-based compensation expense.

  • Raised $110M in October 2024 private placement, with potential for up to $275M upon full warrant exercise, to fund clinical development and operations.

  • Appointed Timothy Pigot as Chief Commercial and Strategy Officer.

  • Scheduled to present at the Jefferies Global Healthcare Conference in November 2025.

Financial highlights

  • Net loss for Q3 2025 was $11.9M ($0.13/share), compared to $5.8M ($0.65/share) in Q3 2024; nine-month net loss was $35.5M ($0.40/share), up from $15.4M ($2.03/share) year-over-year.

  • Research and development expenses rose 82.6% year-over-year to $7.6M for Q3 and 133.9% to $23.4M for the nine months, driven by PAH program and CorHepta acquisition costs.

  • Selling, general and administrative expenses increased 242.7% to $5.6M for Q3 and 197.3% to $16.8M for the nine months, including $1.0M in severance costs.

  • Cash, cash equivalents, and marketable securities totaled $77.3M as of September 30, 2025, down from $97.5M at December 31, 2024.

  • Interest income increased to $838K for Q3 and $2.7M for the nine months, reflecting higher cash balances.

Outlook and guidance

  • Cash runway expected to fund operations for at least the next twelve months from September 30, 2025.

  • Phase 2b IMPROVE-PAH trial for IKT-001 in PAH is expected to begin in Q4 2025, with interim safety review after 12 weeks for at least 50 patients.

  • Anticipates continued increase in R&D and operating expenses as clinical programs advance.

  • No revenue expected until regulatory approval and commercialization of product candidates.

  • Forward-looking statements highlight risks related to trial commencement and execution.

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Frequently asked questions

Inhibikase Therapeutics Inc. is a biopharmaceutical company focused on developing treatments for neurodegenerative diseases and cancers. The company’s research primarily targets diseases related to protein misfolding, such as Parkinson's disease, by aiming to inhibit the malfunction of key cellular processes. Inhibikase Therapeutics develops therapeutics that aim to modify the progression of these diseases and improve patient outcomes. Its approach includes addressing both neurological and oncological conditions through small-molecule therapeutics. The company is headquartered in Atlanta, Georgia, and its shares are listed on the NASDAQ.

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