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Jacobio Pharmaceuticals Group (1167) investor relations material

Jacobio Pharmaceuticals Group H1 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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H1 2025 earnings summary29 Aug, 2025

Executive summary

  • Revenue reached RMB45.7 million for the six months ended June 30, 2025, driven by a milestone payment from the Allist Licensing Agreement, compared to nil in the prior year period.

  • Loss for the period narrowed significantly to RMB59.0 million from RMB169.1 million year-over-year, reflecting reduced R&D and administrative expenses.

  • Achieved NMPA market approval and launch of glecirasib for ≥2L NSCLC in China in May 2025, with strong clinical efficacy and safety data published.

  • Advanced a diversified oncology pipeline, including pan-KRAS, SHP2, BET, Aurora kinase A, p53 Y220C, iADC, and tADC programs, with global and China-based trials ongoing.

  • Entered a licensing agreement with Allist for commercialization and clinical development of glecirasib and sitneprotafib in Greater China, triggering milestone revenue.

Financial highlights

  • Revenue increased to RMB45.7 million from nil, attributable to the Allist Licensing Agreement milestone.

  • R&D expenses decreased 47.3% year-over-year to RMB93.2 million, mainly due to Allist funding pivotal trials.

  • Administrative expenses fell 12.4% to RMB18.6 million, reflecting cost controls and efficiency gains.

  • Net loss for the period was RMB59.0 million, a substantial improvement from RMB169.1 million in the prior year; adjusted loss was RMB56.7 million.

  • Gross profit reached RMB45.7 million, with no cost of revenue recognized.

Outlook and guidance

  • Focus on expanding the KRAS and iADC pipelines, leveraging allosteric inhibitor and iADC platforms for global leadership in oncology.

  • Continued investment in R&D and strategic collaborations to maximize clinical and commercial value.

  • Anticipated completion of key Phase I/II trials and further regulatory submissions in 2026.

  • Expects to utilize remaining IPO proceeds by end of 2025, with resource reallocation to early-stage drug discovery and development.

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Frequently asked questions

Jacobio Pharmaceuticals Group Co., Ltd. is a Chinese biopharmaceutical company focused on innovative drug discovery and development. It concentrates on oncology and immunology, advancing a pipeline of targeted therapies and immune-oncology treatments. The company uses in-house research platforms and conducts clinical trials both domestically and internationally. The company is headquartered in Beijing, China, and its shares are listed on the HKEX.

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