Jade Biosciences
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Jade Biosciences (JBIO) investor relations material

Jade Biosciences Q4 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q4 2025 earnings summary6 Mar, 2026

Executive summary

  • Advanced three pipeline candidates: JADE101 (Phase 1 ongoing, Phase 2 planned), JADE201 (Phase 1 planned), and JADE301 (Phase 1 planned for 2027).

  • Ended 2025 with $336 million in cash, cash equivalents, and investments, providing runway into H1 2028.

  • Completed two private placements in Q4 2025, raising $180 million from healthcare investors.

Financial highlights

  • Cash, cash equivalents, and investments totaled $336.2 million as of December 31, 2025, up from $69.4 million at end of 2024.

  • R&D expenses were $28.5 million in Q4 2025 (up from $17.6 million in Q4 2024) and $93.1 million for full year 2025 (up from $31.2 million for 2024 partial year).

  • G&A expenses were $6.4 million in Q4 2025 (up from $2.4 million in Q4 2024) and $20.4 million for full year 2025 (up from $4.3 million for 2024 partial year).

  • Net loss was $31.9 million in Q4 2025 (vs. $30.1 million in Q4 2024) and $127.4 million for full year 2025 (vs. $47.0 million for 2024 partial year).

  • Interest income for 2025 was $7.8 million; comprehensive loss for 2025 was $127.3 million.

Outlook and guidance

  • JADE101 Phase 1 interim data expected Q2 2026; Phase 2 in IgA nephropathy to begin mid-2026 with preliminary data in 2027.

  • JADE201 first-in-human trial in rheumatoid arthritis to start Q2 2026; interim data in 2027.

  • JADE301 Phase 1 trial expected to commence in H1 2027; further details to be disclosed in H2 2026.

  • Cash runway expected to fund operations into H1 2028.

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