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Edge12 Dec 2025
Running on Clouds: The Story of On
The story of how a Swiss runner's pursuit of a new running sensation became On, aiming to be the most premium global sportswear brand worldwide.
Jade Biosciences (JBIO) investor relations material
Jade Biosciences Registration Filing summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Registration Filing summary22 Dec, 2025
Company overview and business model
Clinical-stage biopharmaceutical company focused on novel biologic therapies for autoimmune diseases, aiming to improve dosing, convenience, safety, and clinical activity.
Lead candidate JADE101 targets APRIL for IgA nephropathy; JADE201 targets BAFF-R for multiple autoimmune disorders.
Pipeline includes a third preclinical program (JADE-003) targeting an undisclosed pathway.
Business model leverages exclusive licensing and collaboration with Paragon Therapeutics for antibody discovery and development.
Financial performance and metrics
No product revenue to date; net loss of $47.0M from inception (June 18, 2024) to Dec 31, 2024, and $95.5M for the nine months ended Sept 30, 2025.
Accumulated deficit of $142.5M as of Sept 30, 2025.
Cash, cash equivalents, and investments totaled $198.9M as of Sept 30, 2025.
Operating expenses driven by R&D ($64.6M for nine months ended Sept 30, 2025) and G&A ($14.0M for same period).
Funded by $95M in convertible notes, $334.2M pre-closing financing, $135M October 2025 PIPE, and $45M December 2025 PIPE.
Use of proceeds and capital allocation
Proceeds from recent private placements used to fund R&D, clinical trials, and general operations.
No proceeds from the resale of shares by the selling stockholder; company bears registration costs.
Cash runway expected to fund operations for at least 12 months from Sept 30, 2025.
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Next Jade Biosciences earnings date
Q4 202526 Mar, 2026
Next Jade Biosciences earnings date
Q4 202526 Mar, 2026
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