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Jaguar Health (JAGX) investor relations material
Jaguar Health 2nd Annual Lytham Partners Healthcare Investor Summit summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Strategic partnerships and licensing
Entered an exclusive license agreement with FuturePak, potentially worth up to $38 million, including $16 million upfront and $20 million in commercial milestones.
FuturePak, through Theratechnologies, will now commercialize Mytesi and Canalevia-CA1, allowing a focus on R&D and pipeline development.
Manufacturing of crofelemer remains in-house, turning it into a profit center.
Business development opportunities remain for blockbuster indications and international animal health markets.
Pipeline and clinical development
Focus shifted to rare disease programs, especially MVID and short bowel syndrome, with clinical trials ongoing.
MVID program may allow for FDA filing by end of this year, with potential approval in 2026 based on single-digit patient trials.
Proof-of-concept data showed up to 39% reduction in parenteral support for MVID and 12-15% for SBS, supporting breakthrough and prime designations.
Short bowel syndrome market estimated at $5–12 billion, with limited competition and high unmet need.
Key milestones include completion of MVID and SBS trials, regulatory filings, and business development deals in 2026.
Regulatory and commercial highlights
Mytesi is the only FDA-approved oral botanical drug for chronic diarrhea in HIV/AIDS and has exclusivity due to botanical guidance.
Canalevia-CA1 received renewed conditional FDA approval for chemotherapy-induced diarrhea in dogs, with a full approval study underway.
Breakthrough and prime designations could accelerate regulatory timelines in the US and EU for rare disease indications.
Investigator-initiated trials and international collaborations are expanding clinical evidence and global reach.
Milestone payments from FuturePak and expanded commercial resources are expected to drive revenue growth.
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