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Jaguar Health (JAGX) investor relations material
Jaguar Health Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary17 Nov, 2025
Executive summary
Net revenue for Q3 2025 was $3.1 million, up 4% sequentially and flat year-over-year, with Mytesi, Gelclair, and Canalevia-CA1 as key products.
Focus on plant-based prescription drugs for GI disorders, with ongoing development of crofelemer for orphan indications (SBS, MVID) and cancer therapy-related diarrhea.
Key clinical and regulatory milestones achieved, including initial trial results for crofelemer in MVID showing up to 37% reduction in parenteral support and FDA meeting for expedited approval.
Business development negotiations and partnerships ongoing to secure non-dilutive funding.
Commercial launch of Gelclair for oral mucositis in cancer patients began in Q4 2024.
Financial highlights
Net revenue for Q3 2025 was $3.1 million, a 4% increase from Q2 2025 and unchanged from Q3 2024; nine-month net revenue was $8.3 million, up 1.2% year-over-year.
Net loss attributable to common shareholders was $9.5 million in Q3 2025, a 4% improvement from $9.9 million in Q3 2024; nine-month net loss was $30.8 million, up from $29.0 million prior year.
Loss from operations increased slightly to $7.3 million in Q3 2025 from $7.2 million in Q3 2024.
Non-GAAP recurring EBITDA net loss improved to $8.9 million from $9.2 million year-over-year.
Cash at period end was $3.5 million, down from $8.0 million at prior year-end.
Outlook and guidance
Anticipates expedited regulatory pathways for orphan indications, with potential NDA filings for two human indications by end of 2026.
Management expects continued losses and negative cash flows; current cash not sufficient to fund operations for 12 months.
Plans to seek additional equity/debt financing and business development partnerships.
Expects to close an animal health partnership in the near term.
Focus on regulatory submissions for crofelemer in metastatic breast cancer and orphan GI indications.
Detail the plan to resolve going concern.
Crofelemer breast cancer trial next steps?
How is FVO debt impacting financials?
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Next Jaguar Health earnings date
Q4 202527 Mar, 2026
Next Jaguar Health earnings date
Q4 202527 Mar, 2026
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Frequently asked questions
Jaguar Health Inc. is a commercial-stage pharmaceutical company focused on developing plant-based gastrointestinal products. The company targets unmet medical needs in human and animal health through proprietary formulations derived from botanical sources. Its development activities support prescription and non-prescription markets. The company is headquartered in San Francisco, California, and its shares are listed on the NASDAQ.
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