KalVista Pharmaceuticals
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KalVista Pharmaceuticals (KALV) investor relations material

KalVista Pharmaceuticals has been acquired

KalVista Pharmaceuticals Q1 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q1 2026 earnings summary14 May, 2026

Executive summary

  • EKTERLY (sebetralstat) received FDA approval in July 2025 and is now marketed in the U.S., Germany, and Japan, with additional global partnerships established.

  • A definitive merger agreement was signed with Chiesi Farmaceutici S.p.A. in April 2026, with the transaction expected to close in Q3 2026.

  • The company operates as a single business segment focused on rare disease therapies.

Financial highlights

  • Total revenues for Q1 2026 were $40.9 million, up from $0 in Q1 2025, driven by EKTERLY's commercial launch.

  • Net loss for Q1 2026 was $23.5 million, a significant improvement from a $51.8 million net loss in Q1 2025.

  • Cash, cash equivalents, and marketable securities totaled $285.0 million as of March 31, 2026.

  • Operating expenses increased to $64.3 million in Q1 2026 from $49.7 million in Q1 2025, mainly due to higher SG&A costs.

  • Research and development expenses decreased by 12% year-over-year to $12.4 million.

Outlook and guidance

  • Management expects continued losses as commercialization of EKTERLY expands.

  • Current liquidity is anticipated to fund operations for at least the next twelve months.

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Frequently asked questions

KalVista Pharmaceuticals Inc. is a biopharmaceutical company engaged in the discovery, development, and commercialization of small molecule protease inhibitors, which are primarily aimed at treating diseases with significant unmet medical needs. The company focuses on advancing a portfolio of inhibitors targeting the kallikrein-kinin system, a key pathway in the human body related to swelling and inflammation. KalVista's research has produced sebetralstat, an oral treatment for hereditary angioedema (HAE), a rare and potentially life-threatening genetic condition characterized by spontaneous episodes of swelling. Additionally, the company is exploring oral Factor XIIa inhibitors, which are in preclinical development stages, for the prophylactic treatment of HAE, along with potential therapies for thrombosis and inflammation. The company is headquartered in Cambridge, Massachusetts, and its shares are listed on the NASDAQ.