LivaNova
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LivaNova (LIVN) investor relations material

LivaNova 44th Annual J.P. Morgan Healthcare Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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44th Annual J.P. Morgan Healthcare Conference summary14 Jan, 2026

Strategic evolution and business focus

  • Refocused on core innovation, winding down non-core programs in 2024 to reallocate resources to core businesses and high-growth opportunities.

  • Portfolio reshaped from 2019–2022, exiting low-growth cardiovascular assets and investing in promising early-stage opportunities.

  • Strategy leverages leadership in epilepsy and cardiopulmonary to enter high-growth neuromodulation markets, including OSA and potentially depression.

  • Two-phase plan: 2025–2028 focuses on core growth and OSA investment; 2028–2030 expects OSA to drive margin expansion.

Core business performance and market dynamics

  • Cardiopulmonary business holds over 70% global share in open heart procedures, with market growth driven by aging populations and surgical complexity.

  • Epilepsy business leads the $700M neuromodulation market, with VNS Therapy transforming over 175,000 lives and benefiting from recent CMS reimbursement increases.

  • Cardiopulmonary and epilepsy markets are underpenetrated, offering significant growth potential through innovation and improved access.

  • Real-world evidence from CORE-VNS shows improved outcomes, supporting further penetration and adoption.

Growth drivers and innovation

  • OSA market entry leverages neuromodulation expertise, targeting patients underserved by current therapies, especially those with complete concentric collapse.

  • OSPREY trial and PolySync algorithm demonstrated high responder rates, including conversion of non-responders, positioning the technology as a clinical game changer.

  • Commercialization strategy for OSA includes a staged approach: initial focus on key opinion leaders, followed by full launch with expanded sales and market access.

  • Synergies with existing infrastructure in manufacturing, R&D, and market access accelerate OSA profitability.

PHGNS's PolySync impact on market penetration
Epilepsy VNS reimbursement impact on volumes
DTD CMS coverage reconsideration timeline
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Frequently asked questions

LivaNova PLC is a global medical technology company that develops and manufactures devices for use in cardiovascular and neuromodulation therapies. The company’s products are designed to address critical conditions such as heart failure, obstructive sleep apnea, and epilepsy. LivaNova’s cardiovascular segment focuses on cardiac surgery and advanced circulatory support, while its neuromodulation segment offers devices for treating neurological disorders. The company is headquartered in London, England, and its shares are listed on the NASDAQ.

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