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Visual21 Nov 2025
Data center suppliers
MapLight Therapeutics (MPLT) investor relations material
MapLight Therapeutics IPO Filing summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.IPO Filing summary6 Oct, 2025
Company overview and business model
Clinical-stage biopharmaceutical company focused on CNS disorders, leveraging a proprietary platform to identify and modulate disease-relevant neural circuits.
Lead candidate ML-007C-MA targets schizophrenia and Alzheimer's disease psychosis (ADP) via M₁/M4 muscarinic agonism, with a precision-matched peripheral antagonist to improve tolerability.
Pipeline includes ML-004 for autism spectrum disorder (ASD), ML-021 for Parkinson’s disease, and ML-009 for hyperactivity/impulsivity disorders, with all programs retaining global rights.
Management team and founders have deep neuroscience and drug development expertise, supported by leading investors and scientific advisors.
Financial performance and metrics
Net losses: $77.6M (2024), $55.7M (2023), $52.2M (H1 2025); accumulated deficit of $251.6M as of June 30, 2025.
Operating expenses: $82.9M (2024), $57.2M (2023), $54.2M (H1 2025), driven by R&D and increased headcount.
Cash, cash equivalents, and short-term investments: $60.5M as of June 30, 2025; $200M raised in Series D preferred stock in July/Sept 2025.
Pro forma net tangible book value post-offering: $12.01/share; immediate dilution to new investors: $4.99/share.
Use of proceeds and capital allocation
Net proceeds from IPO and concurrent private placement estimated at $234.8M.
Planned allocation: $100–120M for ML-007C-MA in schizophrenia (Phase 2), $50–70M for ML-007C-MA in ADP (Phase 2), $15–25M for ML-004 in ASD (Phase 2), $30–40M for preclinical R&D, remainder for working capital and general purposes.
Proceeds expected to fund operations through 2027; additional capital will be needed for regulatory approval and commercialization.
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