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MediWound (MDWD) investor relations material

MediWound Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary20 Nov, 2025

Executive summary

  • Achieved strong execution across strategic, clinical, and operational objectives, positioning for next growth phase.

  • Achieved Q3 2025 revenue of $5.4 million, up 23% year-over-year, driven by higher development services revenue and new DOD contracts.

  • Advanced EscharEx VALUE Phase III trial for venous leg ulcers, with most sites now active and enrolling; FDA-aligned trial design and plans to initiate diabetic foot ulcer trial in H2 2026.

  • Expanded NexoBrid manufacturing facility, increasing production capacity sixfold, with full operational capacity expected by year-end 2025.

  • Strengthened balance sheet with $30 million equity financing from healthcare investors, supporting development and commercialization initiatives.

Financial highlights

  • Q3 2025 revenue was $5.4 million (up 23% YoY), driven by higher development services revenue including DOD contracts.

  • Gross profit for Q3 was $0.9 million (16.5% margin), up from $0.7 million (15.5%) last year.

  • Q3 net loss was $2.7 million ($0.24/share), a significant improvement from $10.3 million ($0.98/share) in Q3 2024, mainly due to non-cash financial income from warrant revaluation.

  • Adjusted EBITDA loss for Q3 was $5.4 million, compared to $3.7 million loss last year.

  • For the first nine months, revenue was $15.1 million (vs. $14.4 million), gross profit $3 million (19.7% margin), net loss $16.7 million ($1.53/share), improved from $26.3 million ($2.72/share) last year.

Outlook and guidance

  • Monitoring EU regulatory adjustments for EscharEx VLU trial; will update guidance as visibility improves.

  • Diabetic foot ulcer (DFU) program to initiate in H2 2026, pending EMA feedback and protocol alignment.

  • Expect full operational capacity at new NexoBrid facility by year-end 2025, with regulatory review determining commercial output timing.

  • BARDA and DOD-related revenue timing for Q4 uncertain due to recent government shutdown; activities expected to resume.

  • Market access and pricing assessment estimates peak sales opportunity for EscharEx at $831 million.

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Frequently asked questions

MediWound Ltd. specializes in the development, manufacture, and commercialization of innovative therapies for tissue repair and regeneration. The company focuses primarily on enzymatic debridement solutions for the treatment of severe burns, chronic wounds, and other hard-to-heal injuries. MediWound's proprietary technologies are designed to improve the healing process by selectively removing dead or damaged tissue without harming surrounding healthy tissue. The company serves healthcare providers, hospitals, and wound care centers globally, aiming to enhance patient outcomes and reduce treatment costs. MediWound is headquartered in Yavne, Israel, and its shares are listed on the NASDAQ.

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