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Investor Relations14 Oct 2025
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Nektar Therapeutics (NKTR) investor relations material
Nektar Therapeutics Stifel Virtual Immunology and Inflammation Forum summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Stifel Virtual Immunology and Inflammation Forum summary15 Sep, 2025
Company overview and scientific focus
Focuses on immune science, particularly regulatory T cell (Treg) biology, to treat autoimmune and chronic inflammatory diseases.
Tregs maintain peripheral tolerance and prevent autoimmune disease; dysfunction leads to disease onset.
Approach aims to restore Treg function, rebalancing the immune system and controlling disease pathology.
ResPEG development and differentiation
ResPEG (formerly NKTR-358) was developed using in vivo phenotypic screening for optimal Treg mobilization and durable signaling.
Functions as a full agonist of the IL-2 receptor, providing sustained Treg activation without oversignaling.
Over 1,000 subjects have been exposed to ResPEG, with consistent pharmacokinetics and pharmacodynamics across multiple studies.
Clinical trial design and results
Phase 2b atopic dermatitis trial enrolled 393 biologic-naive patients with moderate to severe disease, randomized to three ResPEG dosing regimens or placebo.
Primary endpoint was EASI percent change from baseline at week 16; secondary endpoints included EASI-75, validated IgA, and itch response.
Results replicated and extended phase 1b findings, showing dose-dependent efficacy and durable disease control post-treatment.
ResPEG's AD remission potential
ISRs impact on ResPEG patient adherence
What defines ResPEG's success in alopecia?
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Next Nektar Therapeutics earnings date
Q3 20256 Nov, 2025
Next Nektar Therapeutics earnings date
Q3 20256 Nov, 2025
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Leroy DaleyApp Store
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
Eferix Drawings Google Play
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Frequently asked questions
Nektar Therapeutics is an American biopharmaceutical company that specializes in the discovery and development of novel therapies. These therapies aim to selectively modulate the immune system to treat autoimmune disorders, chronic inflammatory conditions, and cancer.The company uses proprietary PEGylation and advanced polymer conjugate technologies to modify the chemical structure of substances, facilitating the development of new drug candidates. It is headquartered in San Francisco, California, and its shares are listed on the NASDAQ under the ticker symbol NKTR.
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