)
Edge28 Nov 2025
Keeping the Streak Alive: The Story of Duolingo
How Duolingo made language learning addictive, scaled to millions of users, and built a powerful subscription business around everyday practice.
Neurogene (NGNE) investor relations material
Neurogene Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary13 Nov, 2025
Executive summary
NGN-401 for Rett syndrome advanced to a registrational trial, with positive interim Phase 1/2 data showing multidomain, durable gains and a favorable safety profile at the 1E15 vg dose; higher dose discontinued after a fatal SAE.
First participant dosed in the Embolden trial, with full enrollment expected in 3–6 months across 13 sites and FDA alignment on design and endpoints.
NGN-101 for CLN5 Batten disease deprioritized after FDA denied RMAT designation; options for the program are being evaluated.
In-house cGMP manufacturing facility in Houston is operational, supporting clinical and preclinical supply.
NGN-401 received multiple regulatory designations, including RMAT, orphan drug, Fast Track, rare pediatric, PRIME, and ILAP.
Financial highlights
Net loss of $65.6 million for the nine months ended September 30, 2025, and $21.0 million for Q3 2025; net loss per share was $(3.11) for nine months and $0.99 for Q3.
Cash, cash equivalents, and short-term investments totaled $265.4 million as of September 30, 2025.
R&D expenses increased to $54.4 million for nine months and $17.2 million for Q3 2025, mainly due to NGN-401 clinical and CMC costs.
G&A expenses rose to $21.4 million for nine months and $6.6 million for Q3 2025, driven by higher headcount and stock-based compensation.
Licensing revenue of $0.9 million recognized in the nine months and Q3 2025.
Outlook and guidance
Cash runway expected to fund operations through at least Q1 2028; additional capital will be needed for commercialization and pipeline expansion.
Embolden trial for NGN-401 expected to complete enrollment in 3–6 months.
Ongoing evaluation of options for NGN-101 and early discovery programs.
NGN-401 ICV delivery advantages over IT-L
R&D spend allocation changes and rationale?
Embolden site conversion to commercial status?
Partial view of Summaries dataset, powered by Quartr API
Research faster. Power your platform.
Next Neurogene earnings date
Q4 202519 Mar, 2026
The essential earnings season companion
The #1 app for qualitative research. Live earnings calls, AI chat, transcripts, and more. All for free.
Live calls and transcripts
Listen to earnings calls, CMDs, investor conferences, and more – with a podcast-like experience.
Find what you need faster
Search for any keyword across all transcripts simultaneously.
Easily store key findings
Capturing important takeaways is as simple as it gets. Even during your lunch run or commute.
Your watchlist. Your dashboard.
Follow the companies that matter to you. Get a personalized feed with real-time updates.
Be the first to know
Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned.
Consensus estimates
Access analyst consensus estimates, valuation multiples, and revenue segments splits.
All IR material in one place
The easiest way to stay updated during earnings season.
Global coverage
All events from public companies. Live and recorded.
Just click and listen
No webcast links. No manual registrations.
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
)
Leroy DaleyApp Store
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
)
Eferix Drawings Google Play
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
anuj283App Store
excellent app, it gives me free access to company earnings calls and annual reports. I also love the convenience of calls being available offline so I can listen in whilst doing other things and even when internet or WiFi isn't available.
Leroy DaleyApp Store
One of the very few apps you could call perfect. If something was to add to it, maybe the share price of the company when you search for it, but it's already excellent.
Eferix Drawings Google Play
This is genuinely one of the cleanest and fastest finance apps out there to track the market.
anuj283App Store
I can't remember the last time an app had such a positive impact on my investment process.
)
@ankurshah47_ x.com
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
Amina0781App Store
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
@theshortbearx.com
I can't remember the last time an app had such a positive impact on my investment process.
@ankurshah47_ x.com
Love the app! Quartr makes it really easy to keep track of earnings calls. It also includes the reports and slides to make it easier to follow along.
Amina0781App Store
Quartr is amazing, no way around it. It is the best right now for earnings calls, presentations, and the like.
@theshortbearx.com
)
)
Frequently asked questions
Neurogene Inc. (NGNE) is a clinical-stage biotechnology company focused on developing genetic medicines for rare neurological diseases. Utilizing its proprietary transgene regulation technology, known as Expression Attenuation via Construct Tuning (EXACT), Neurogene aims to address high unmet medical needs that are not effectively treated by conventional gene therapies. The company is headquartered in New York, New York, and its shares are listed on the NASDAQ.
Quartr provides global coverage of all investor relation material from public companies.
Mobile app: Research anytime, anywhere with the #1 app for live earnings calls, transcripts, analyst estimates, and more. All for free.
Desktop (Quartr Pro): The leading platform for qualitative research, used daily by top firms and financial institutions.
Quartr API: Build custom solutions powered by live earnings calls, live transcripts, filings and reports, slide presentations, and more.
Yes, the Quartr mobile app is free on both iOS and Android.
Yes. Quartr provides global, industry-leading live coverage of company events such as regular earnings calls, capital markets days, M&A announcements, and investor conferences. Live with zero delays. Just click and listen.
Yes, capturing important takeaways is as simple as it gets. Even during your lunch run or commute.
Yes. Follow the companies that matter to you. Get a personalized feed with real-time updates, a tailored earnings calendar, and instant alerts when earnings calls go live.
Yes. Set keyword alerts for any company, product, or competitor. Get notified the moment they're mentioned, regardless of who's talking.
Explore our global coverage