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Orexo (ORX) investor relations material
Orexo Investing in Life Science 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Investing in Life Science 2025 summary25 Sep, 2025
Strategic direction and business overview
Expanding beyond opioid use disorder into new therapeutic areas and technologies.
Maintains ongoing sales with four products on the market and annual revenues near SEK 600 million.
Focus shifting to the Amorphox platform for next-generation drug delivery and product development.
Subsolve generates stable revenue in the US and Europe, with cost reductions expected from new manufacturing processes.
Older products continue to provide royalty income, while the pipeline is prioritized for future growth.
Pipeline and product development
Icepri (OX124), a high-dose naloxone rescue medication, is preparing for FDA filing next year after resolving manufacturing and stability requirements.
OX125 (nalmefene) development is paused pending market trends, while OX390 targets emerging overdose risks from mixed substances like silacine.
Collaboration with US authorities is underway for OX390 development; OX640 (epinephrine) shows faster uptake and greater stability than current products.
OX640's powder form offers advantages in shelf life and portability, with ongoing partnership discussions for commercialization.
Amorphox technology platform
Amorphox enables stable encapsulation and nasal delivery of both small and large molecules, including vaccines and peptides.
Demonstrated high stability at elevated temperatures and rapid, efficient uptake in clinical studies.
Animal studies with semaglutide show sevenfold higher nasal uptake versus oral tablets and more consistent bioavailability.
Eliminates cold chain requirements, attracting significant attention and opening new project opportunities.
Amorphox GLP-1 commercialization plan?
OX-124 commercial strategy post-OTC shift?
Subsol asset: Future strategy for value?
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Next Orexo earnings date
Q3 202523 Oct, 2025
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Frequently asked questions
Orexo AB, a specialty pharmaceutical company, develops and commercializes pharmaceuticals and digital therapies in the United States. The Company's strategy is to focus on developing products that reduce the risk of opioid dependence, misuse and accidental ingestion by chronic pain patients in need of effective pain management for long-lasting pain, who have been historically underserved. Furthermore, the company is differentiated by their scientifically-validated medications that treat lower urinary tract symptoms due to benign prostatic hyperplasia (BPH). The company's mission is to improve the lives of patients through acquisition, development and commercialization of new therapies as quickly as possible, with a focus on digital health technologies to rapidly deliver greater access to leading edge therapies.
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