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Organogenesis (ORGO) investor relations material
Organogenesis Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Achieved record Q4 and FY 2025 revenue, with Q4 net product revenue of $225.1 million (up 78% YoY) and FY 2025 revenue of $563.0 million (up 17% YoY), driven by 83% YoY growth in advanced wound care sales.
Net income rose to $43.7 million in Q4 2025 from $7.7 million in Q4 2024; FY 2025 net income was $37.0 million, up from $0.9 million in FY 2024.
Navigated significant CMS policy changes, shifting reimbursement to PMA products and supporting innovation and higher-value offerings.
Faced market disruption and clinician confusion in early 2026 due to CMS commentary and withdrawal of LCD coverage, impacting utilization of PMA-approved products.
Advanced strategic initiatives, including a new manufacturing and R&D center and progress on the ReNu program targeting knee osteoarthritis.
Financial highlights
Q4 2025 net product revenue was $225.1 million, up 78% year-over-year and 50% sequentially; FY 2025 revenue was $563.0 million, up 17% year-over-year.
Advanced wound care revenue reached $217.2 million in Q4 (up 83% YoY); Surgical and Sports Medicine revenue was $7.9 million in Q4 (down 2% YoY).
Gross profit for Q4 was $175.2 million (78% margin), up from 75% last year; FY 2025 gross margin was 76%.
Operating income for Q4 was $63.3 million, up 519% YoY; FY 2025 operating income was $44.7 million, reversing a loss in FY 2024.
Adjusted EBITDA for Q4 was $84.2 million (37% margin), up from $18.2 million last year; FY 2025 adjusted EBITDA was $98.1 million.
Outlook and guidance
FY 2026 net revenue guidance is $350–$420 million, a 25–38% decline from FY 2025, reflecting anticipated short-term disruption from CMS reimbursement changes.
Q1 2026 revenue projected to decline ~50% YoY; first-half revenue expected to decline 30%-35%.
Sequential revenue growth anticipated in Q3 and Q4 2026, with positive adjusted EBITDA and high teens EBITDA margins in Q4.
Management expects normalized annual growth post-2026, with recovery and normalized growth anticipated in 2027.
- Strong product innovation and regulatory adaptation drive growth amid reimbursement shifts.ORGO
2024 Cantor Fitzgerald Global Healthcare Conference3 Feb 2026 - Q2 revenue up 11% to $130.2M, but net loss widened on impairments and write-downs.ORGO
Q2 20241 Feb 2026 - Q3 net income rose to $12.3M on 6% revenue growth; 2024 outlook strong despite regulatory risks.ORGO
Q3 202414 Jan 2026 - Regulatory changes, new launches, and a robust pipeline position the company for strong future growth.ORGO
Cantor Global Healthcare Conference 20255 Jan 2026 - Regenerative medicine firm seeks to raise $250M and enable resale of 50M shares by holders.ORGO
Registration Filing16 Dec 2025 - Registering 130,000 Series A Preferred and 34.3M Common Shares for resale by private investors.ORGO
Registration Filing16 Dec 2025 - Annual meeting to vote on directors, executive pay, major stock issuance, and auditor ratification.ORGO
Proxy Filing2 Dec 2025 - Key votes on director elections, executive pay, major stock issuance, and auditor ratification.ORGO
Proxy Filing2 Dec 2025 - Q4 revenue up 27% year-over-year; FY 2025 guidance signals growth despite LCD headwinds.ORGO
Q4 20241 Dec 2025
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