Ovid Therapeutics
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Ovid Therapeutics (OVID) investor relations material

Ovid Therapeutics TD Cowen 46th Annual Health Care Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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TD Cowen 46th Annual Health Care Conference summary4 Mar, 2026

Strategic focus and pipeline overview

  • Focused on central nervous system disorders, targeting neural excitation and inhibition balance with small molecule medicines.

  • Pipeline built around differentiated mechanisms, aiming for step-change therapeutic and commercial potential.

  • Next 6–18 months expected to bring significant data readouts and progress across all assets.

OV329 epilepsy program

  • OV329 inhibits GABA aminotransferase, increasing GABA levels and enhancing brain inhibition.

  • Recent biomarker data showed brain inhibition at therapeutic levels, with better tolerability than current seizure drugs.

  • No anticipated drug-drug interactions or titration challenges; targeting both focal onset and pediatric epilepsies.

  • Phase II placebo-controlled study with a 7mg dose to begin soon; safety and tolerability data expected imminently.

  • Open-label proof-of-concept study in seizure patients to read out by year-end; expansion into developmental epileptic encephalopathies considered.

OV329 differentiation and safety

  • Only company pursuing GABA aminotransferase inhibition for seizures; mechanism differs from sodium/potassium channel drugs.

  • OV329 avoids the retinal toxicity seen with first-generation drug Sabril due to different tissue partitioning and rapid clearance.

  • Safety and tolerability profile supported by animal and human studies; mild, transient side effects observed.

  • Targeting competitive seizure reduction (mid-30% to 50% from baseline) with strong tolerability.

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Leerink Global Healthcare Conference 202611 Mar, 2026
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Frequently asked questions

Ovid Therapeutics Inc. is a biopharmaceutical company focused on developing treatments for rare neurological disorders. The company specializes in small-molecule and genetic-based therapies targeting conditions such as epilepsies and neurodevelopmental syndromes. Its research and development efforts aim to advance novel drug candidates through clinical trials and regulatory approvals. The company is headquartered in New York, New York, and its shares are listed on the NASDAQ.

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