Pacira BioSciences
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Pacira BioSciences (PCRX) investor relations material

Pacira BioSciences Q4 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q4 2025 earnings summary26 Feb, 2026

Executive summary

  • 2025 revenue reached $726.4 million, the highest in company history, with gross margins achieving a record 81% and over 2.5 million patients served.

  • Achieved 7% EXPAREL volume growth, with top 5 states accounting for 40% of procedural volumes and strong Q4 performance.

  • Strategic partnerships, including J&J MedTech and LG Chem, expanded access in Asia-Pacific, with ex-U.S. revenue expected from 2027.

  • Launched the 5x30 strategy: targeting 3 million patients annually, five new pipeline programs, and five strategic partnerships by 2030.

  • Advanced robust pipeline with multiple programs entering data-rich phases and key clinical milestones expected in 2026.

Financial highlights

  • FY25 revenue was $726.4 million, with Q4 revenue at $196.9 million, up 4–5% year-over-year.

  • Q4 EXPAREL sales were $155.8 million (+5% YoY), ZILRETTA $33.0 million (flat), iovera° $7.0 million (+8% YoY).

  • Non-GAAP gross margin for FY25 was 81%; Q4 non-GAAP gross margin was 80%.

  • Adjusted EBITDA for FY25 was $186.5 million; Q4 adjusted EBITDA was $38.7 million.

  • Ended 2025 with $238 million in cash and investments.

Outlook and guidance

  • 2026 revenue guidance: $745–$770 million; EXPAREL sales expected at $600–$620 million.

  • Non-GAAP gross margin projected at 77–79%; R&D expense at $105–$115 million; SG&A at $320–$340 million.

  • Ex-U.S. revenue expected to begin in 2027 as regulatory filings proceed in Asia-Pacific.

  • Pipeline poised for multiple clinical data readouts in 2026, including PCRX-201 and PCRX-2002.

  • Quarterly sales trends to follow historical patterns, with Q1 slightly lower due to weather impacts.

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Next Pacira BioSciences earnings date

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Barclays 28th Annual Global Healthcare Conference11 Mar, 2026
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Barclays 28th Annual Global Healthcare Conference11 Mar, 2026

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Frequently asked questions

Pacira BioSciences Inc. is a pharmaceutical company focused on developing and commercializing non-opioid pain management and regenerative health solutions. The company's primary offerings include products designed to provide long-lasting pain relief for patients undergoing surgical procedures. Pacira BioSciences serves the healthcare sector, working with hospitals, ambulatory surgery centers, and healthcare providers to reduce reliance on opioids and improve patient outcomes through its innovative treatments. The company is headquartered in Tampa, Florida, and its shares are listed on the NASDAQ.

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