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Pacira BioSciences (PCRX) investor relations material
Pacira BioSciences Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Achieved 6% year-over-year revenue growth in Q3 2025, driven by strong EXPAREL and iovera° performance, with ZILRETTA showing modest growth and veterinary product sales fluctuating due to order timing.
Treated over 3 million patients annually, focusing on musculoskeletal pain and adjacent markets, while transitioning to an innovative biopharmaceutical organization.
Expanded clinical pipeline with in-licensing of AMT-143, a long-acting non-opioid pain therapy, and completed the acquisition of GQ Bio Therapeutics.
Strengthened intellectual property with the 21st EXPAREL patent listed in the FDA Orange Book, extending exclusivity to July 2044.
Implemented cost-saving measures, including workforce reduction and decommissioning a manufacturing suite, resulting in $3.7 million in restructuring charges and anticipated $13 million in annual savings.
Financial highlights
Q3 2025 net product sales reached $179.5 million, with EXPAREL at $139.9 million, ZILRETTA at $29.0 million, and iovera° at $6.5 million.
Gross margin improved to 82% non-GAAP (81% GAAP), up from 78% prior year, driven by manufacturing efficiencies and lower inventory reserves.
Adjusted EBITDA for Q3 2025 was $49.4 million.
Net income for Q3 2025 was $5.4 million ($0.12 per share), compared to a net loss in Q3 2024.
Ended Q3 2025 with $246.3 million in cash and investments.
Outlook and guidance
Full-year 2025 revenue guidance narrowed to $725–$735 million, with non-GAAP gross margin guidance raised to 80–82% (from 78–80%).
Non-GAAP R&D expense expected at $95–$105 million; SG&A at $310–$320 million.
Management targets double-digit compounded annual product revenue growth through 2030 and expects annual operating expense reduction of $13 million from restructuring.
Anticipates reporting interim results from the Phase 2 ASCEND study of PCRX-201 for knee osteoarthritis before the end of 2026.
Sufficient liquidity to fund operations and capital needs for at least the next 12 months.
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