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Pacira BioSciences (PCRX) investor relations material

Pacira BioSciences Q2 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q2 2025 earnings summary5 Aug, 2025

Executive summary

  • Achieved total Q2 2025 revenues of $181.1M, with strong execution across corporate, clinical, and commercial initiatives, supporting the five by 30 growth strategy and leadership in musculoskeletal pain.

  • EXPAREL and ZILRETTA drove growth, with over 3M patients treated annually and double-digit compounded annual product revenue growth.

  • Net loss for Q2 2025 was $4.8M, primarily due to higher operating expenses and one-time legal settlement costs; non-GAAP net income was $36.0M.

  • Strategic initiatives included the acquisition of GQ Bio Therapeutics, a co-promotion agreement with J&J MedTech for ZILRETTA, and a reduction in force to optimize manufacturing.

  • Repurchased 2.0M shares for $50M; ended Q2 with $445.9M in cash, pro forma $270M after debt repayment and royalty receipt.

Financial highlights

  • Q2 2025 revenues rose to $181.1M from $178.0M year-over-year; EXPAREL sales grew 4.4% to $142.9M, ZILRETTA up 2% to $31.3M, iovera° $5.6M.

  • Non-GAAP gross margin improved to 82% from 76% year-over-year; GAAP gross margin 77% (up from 75%).

  • Adjusted EBITDA for Q2 was $54.3M; adjusted EBITDA margin approximately 30% of revenue.

  • Operating expenses rose to $172.6M, driven by higher R&D and SG&A.

  • Cash and investments: $445.9M at quarter-end, pro forma $270M after debt repayment.

Outlook and guidance

  • 2025 total revenue guidance narrowed to $730M–$750M (prior $725M–$765M); non-GAAP gross margin raised to 78–80% (prior 76–78%).

  • Non-GAAP R&D expense expected at $90M–$105M; SG&A at $290M–$320M; stock-based compensation $56M–$61M.

  • Continued investment in clinical programs, commercial expansion, and manufacturing enhancements for EXPAREL, ZILRETTA, and iovera°.

  • Expect sustainable earnings growth driven by sales, margin expansion, and share repurchases.

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Frequently asked questions

Pacira BioSciences Inc. is a pharmaceutical company focused on developing and commercializing non-opioid pain management and regenerative health solutions. The company's primary offerings include products designed to provide long-lasting pain relief for patients undergoing surgical procedures. Pacira BioSciences serves the healthcare sector, working with hospitals, ambulatory surgery centers, and healthcare providers to reduce reliance on opioids and improve patient outcomes through its innovative treatments. The company is headquartered in Tampa, Florida, and its shares are listed on the NASDAQ.

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