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PMV Pharmaceuticals (PMVP) investor relations material
PMV Pharmaceuticals Q3 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Rezatapopt remains the lead precision-oncology program; no product revenue, with substantial R&D spending and recurring losses.
PYNNACLE Phase 2 ovarian cancer primary-analysis enrollment is complete; Q1 2027 accelerated-approval NDA submission is planned.
Rezatapopt showed a 46% investigator-assessed ORR in the ovarian efficacy population; a pivotal-cohort update is planned for a late-breaking ENA 2026 presentation.
Financial highlights
Q3 R&D was $16.1M and G&A $4.0M; operating expenses were $20.1M, down from $22.5M YoY.
Q3 net loss was $34.4M vs. $21.1M YoY; 2026 included a $12.8M warrant fair-value loss and $2.3M in warrant-related offering costs.
9M R&D was $46.1M vs. $54.1M, G&A $11.9M vs. $12.9M, and net loss $70.5M vs. $59.7M.
9M operating cash use was $52.4M vs. $56.4M in 2025; no product revenue has been generated.
Outlook and guidance
Cash, cash equivalents and marketable securities of $108.5M are expected to fund planned operations into Q1 2028; estimates depend on assumptions that may prove incorrect.
Initial accelerated-approval NDA submission for rezatapopt in platinum-resistant/refractory ovarian cancer is planned for Q1 2027.
PYNNACLE ovarian-cohort primary-analysis data and cohort updates are planned for a late-breaking oral presentation at ENA 2026.
Operating expenses and losses are expected to remain substantial as clinical development, regulatory work and commercialization preparation advance.
- Ovarian cancer data support a planned 1Q2027 rezatapopt NDA, with cash runway into 1Q2028.PMVP
Corporate presentation - Rezatapopt demonstrates strong efficacy in PROC with launch and expansion plans well underway.PMVP
H.C. Wainwright 28th Annual Global Investment Conference - Phase 2 trial completed, NDA planned Q1 2027, cash runway into Q2 2027, funding risks persist.PMVP
Q2 2026 - Interim phase II data for Y220C p53 solid tumors expected July-August, with robust enrollment.PMVP
TD Cowen's 6th Annual Oncology Innovation Summit - Directors elected, executive pay approved, and auditor ratified; all proposals passed.PMVP
AGM 2026 - Q1 2026 net loss was $18.0M; cash runway extends through Q2 2027 as rezatapopt advances in trials.PMVP
Q1 2026 - Rezatapopt shows 46% ORR in ovarian cancer; NDA submission planned for Q1 2027.PMVP
TD Cowen 46th Annual Health Care Conference - Key votes include director elections, executive pay, and auditor ratification.PMVP
Proxy filing - Director elections, executive pay, and auditor ratification headline the annual meeting agenda.PMVP
Proxy filing
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