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Edge29 May 2026
Who You Gonna Call? The Story of Rollins
How Rollins built one of America's most consistent businesses through recurring pest control, trusted local brands, and decades of acquisitions.
ProMIS Neurosciences
ProMIS Neurosciences (PMN) investor relations material
ProMIS Neurosciences Jefferies Global Healthcare Conference 2026 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Jefferies Global Healthcare Conference 2026 summary4 Jun, 2026
Corporate and financial overview
Clinical-stage company focused on protein misfolding, with a strong financial position following a $75 million capital raise and potential for an additional $100 million upon data readout; cash runway extends through 2027.
Leadership team includes seasoned experts in neurodegenerative diseases and drug discovery.
Technology platform and differentiation
Proprietary EpiSelect platform uses computational modeling and AI to design antibodies highly selective for misfolded proteins, targeting 3D epitopes unique to toxic oligomers.
Approach avoids off-target binding, aiming for improved efficacy and safety compared to conventional antibodies.
Clinical program and trial design
Lead asset PMN310 targets toxic amyloid beta oligomers in Alzheimer's, avoiding plaque and monomers to reduce ARIA risk and improve efficacy.
Phase I-A study in healthy volunteers showed strong safety, tolerability, and sufficient blood-brain barrier penetration.
Ongoing placebo-controlled, double-blind, randomized phase Ib study in Alzheimer's patients at 22 U.S. sites, fully enrolled with 144 subjects, dosing monthly for 12 months.
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Latest events from ProMIS Neurosciences
- Board elections, clinical trial progress, and major financing mark a pivotal year.PMN
AGM 202620 May 2026 - Q1 2026 net loss $8.2M, $175M PIPE closed, Alzheimer's trial milestones on track.PMNQ1 202612 May 2026
- PMN310 targets toxic amyloid-beta in Alzheimer's, with pivotal data expected in 2026.PMNInvestor presentation12 May 2026
- Phase 1b Alzheimer's trial fully enrolled; key data and platform validation expected this year.PMNGuggenheim Securities Emerging Outlook: Biotech Summit 202613 Apr 2026
- Shareholders will vote on board elections, auditor ratification, and expanding the stock option plan.PMNProxy filing9 Apr 2026
- Election of directors, auditor ratification, and stock plan amendment up for vote in May 2026.PMNProxy filing9 Apr 2026
- Up to $200M in securities, including $50M ATM, to fund neurodegenerative drug development.PMNRegistration filing25 Mar 2026
- PRECISE-AD trial fully enrolled; strong safety, major financing, and top-line data expected 2027.PMNQ4 202525 Mar 2026
- Biotech registers 13.8M shares for resale after $75.5M private placement to fund clinical trials.PMNRegistration Filing18 Mar 2026
Next ProMIS Neurosciences earnings date
Q2 202611 Aug, 2026
ProMIS Neurosciences
Next ProMIS Neurosciences earnings date
Q2 202611 Aug, 2026
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Amina0781App Store
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@theshortbearx.com
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