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Protara Therapeutics
Protara Therapeutics (TARA) investor relations material
Protara Therapeutics Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q4 2025 earnings summary10 Mar, 2026
Executive summary
Reported interim data from ADVANCED-2 trial in NMIBC; TARA-002 showed a 68% complete response rate at six months in BCG-unresponsive patients.
Received Breakthrough Therapy and Fast Track designations for TARA-002 in lymphatic malformations; regulatory update expected in 1H 2026.
Completed an $86 million public offering, extending cash runway into 2028.
Financial highlights
Cash, cash equivalents, and investments totaled $197.9 million as of December 31, 2025.
Research and development expenses rose to $13.1 million in Q4 2025 (from $9.5 million in Q4 2024) and $42.6 million for the year (from $31.7 million in 2024).
General and administrative expenses increased to $6.0 million in Q4 2025 (from $4.8 million in Q4 2024) and $21.9 million for the year (from $17.5 million in 2024).
Net loss for Q4 2025 was $17.3 million ($0.37/share) vs. $12.8 million ($0.48/share) in Q4 2024; full-year net loss was $57.4 million ($1.34/share) vs. $44.6 million ($2.17/share) in 2024.
Outlook and guidance
Enrollment for the BCG-unresponsive cohort in ADVANCED-2 expected to complete in 2H 2026.
ADVANCED-3 registrational trial in BCG-naïve patients set to initiate in 2H 2026.
Interim results from THRIVE-3 trial of IV Choline Chloride expected in 2H 2026.
Cash runway projected to support operations into 2028.
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Latest events from Protara Therapeutics
- TARA-002 leads in NMIBC efficacy, with pivotal trials and regulatory milestones ahead in 2024.TARA
TD Cowen 46th Annual Health Care Conference3 Mar 2026 - Late-stage data and regulatory progress position TARA-002 and IV Choline Chloride for broad impact.TARAOppenheimer 36th Annual Healthcare Life Sciences Conference26 Feb 2026
- Strong efficacy, durability, and safety for TARA-002 in NMIBC with high response rates.TARAStudy update24 Feb 2026
- TARA-002 and IV Choline advance in pivotal studies, with key data and catalysts expected by 2026.TARAH.C. Wainwright 26th Annual Global Investment Conference 202421 Jan 2026
- Late-stage oncology and rare disease programs advance toward key data and regulatory milestones.TARA44th Annual J.P. Morgan Healthcare Conference15 Jan 2026
- TARA-002 and IV Choline advance as late-stage therapies for high unmet needs in oncology and rare disease.TARACorporate presentation14 Jan 2026
- TARA-002 and IV Choline advance in pivotal trials, targeting major unmet needs in oncology and rare disease.TARAGuggenheim Securities Inaugural Healthcare Innovation Conference14 Jan 2026
- 100% six-month complete response in BCG-unresponsive NMIBC, strong durability, no serious AEs.TARAStudy Update11 Jan 2026
- TARA-002 and IV choline advance in late-stage trials, showing strong efficacy and safety data.TARA43rd Annual J.P. Morgan Healthcare Conference 202510 Jan 2026
Next Protara Therapeutics earnings date
Q1 20261 May, 2026
Protara Therapeutics
Next Protara Therapeutics earnings date
Q1 20261 May, 2026
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Amina0781App Store
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