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RAPT Therapeutics (RAPT) investor relations material
RAPT Therapeutics Stifel Virtual Immunology and Inflammation Forum summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Stifel Virtual Immunology and Inflammation Forum summary15 Sep, 2025
Company overview and lead asset
Focus on developing high-value therapeutics for inflammatory disorders, targeting large markets in food allergy and chronic spontaneous urticaria.
Lead asset RPT-904, a next-generation anti-IgE antibody, in-licensed from Gemincare, is in phase 2 development.
RPT-904 aims to improve upon omalizumab (Xolair) with better dosing convenience and broader patient coverage.
Portfolio includes a next-generation CCR4 antagonist, with a new candidate selected and advancing toward the clinic.
RPT-904 deal terms and market opportunity
$35 million upfront payment, up to $670 million in milestones, with $450 million as commercial milestones.
Royalty rates reach low double digits; rights are worldwide except China.
Food allergy and urticaria markets estimated at $40 billion and $5 billion, respectively.
Over 60,000 patients on Xolair for food allergy within a year of approval, indicating high unmet need.
Differentiation and competitive landscape
RPT-904 designed for longer half-life (YTE mutation), improved affinity, and less frequent dosing (Q8 or Q12 weeks vs. Q2 weeks for Xolair).
Shares the same epitope as omalizumab, unlike failed competitor ligelizumab, supporting higher confidence in efficacy.
Competitive landscape includes other IgE antibodies and novel approaches, but RPT-904 is among the most advanced.
904's label for high IgE/weight patients?
Gemincare CSU data impact on US/EU Phase 3?
Confidence in next-gen CCR4 safety profile?
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Next RAPT Therapeutics earnings date
Q3 202511 Nov, 2025
Next RAPT Therapeutics earnings date
Q3 202511 Nov, 2025
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Frequently asked questions
RAPT Therapeutics Inc. is a clinical-stage biopharmaceutical company specializing in immunology-based treatments. The company's primary focus is on discovering, developing, and commercializing oral small molecule therapies for significant unmet needs in inflammatory diseases and cancer. Utilizing a proprietary drug discovery and development engine, RAPT Therapeutics designs highly selective small molecules aimed at modulating critical immune responses. The company's pipeline includes drug candidates targeting CCR4 and other key immune pathways, with ongoing development for conditions such as atopic dermatitis and various cancers. RAPT Therapeutics is headquartered in South San Francisco, California, and its shares are listed on the NASDAQ.
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