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RAPT Therapeutics (RAPT) investor relations material
RAPT Therapeutics 44th Annual J.P. Morgan Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Strategic focus and pipeline development
Focused on transformative therapies for high-value inflammatory disorders, with Ozureprobart as the lead asset targeting allergic diseases.
Ozureprobart is a next-generation anti-IgE antibody designed for less frequent dosing and broader efficacy than current therapies.
Expanded pipeline includes a next-generation CCR4 antagonist and ongoing collaborations with partners in China for asthma and CSU studies.
Board and team strengthened with experienced industry leaders to support commercialization and drug development.
Completed a $265 million follow-on offering, extending cash runway to mid-2028.
Clinical progress and milestones
Phase 2b food allergy study (PRESTIGE) initiated, with top-line data expected in the first half of 2027.
Positive phase 2 results in chronic spontaneous urticaria (CSU) support initiation of phase 3 studies in both the US and China in 2024.
Partner JU in China completed a phase 2 asthma study and plans to start phase 3 trials in CSU and asthma this year.
Multiple clinical milestones anticipated over the next two years, supported by a strong cash position.
Enrollment for PRESTIGE is on track, with high investigator and patient interest across US, Canada, and Australia.
Differentiation and market opportunity
Ozureprobart offers less frequent dosing (every 8–12 weeks) compared to Omalizumab (every 2–4 weeks), reducing injection burden.
Higher potency and improved PK allow treatment of high-IgE and high-weight patients, addressing unmet needs excluded from Omalizumab label.
Market research indicates payers value the improved compliance and broader efficacy, supporting a price premium over branded Omalizumab.
Food allergy represents a $40B+ US market, with 17 million diagnosed patients and high socioeconomic burden.
Omalizumab’s rapid uptake in food allergy highlights high unmet need and commercial potential for next-generation therapies.
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