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Rocket Pharmaceuticals (RCKT) investor relations material
Rocket Pharmaceuticals Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Advanced three cardiovascular gene therapy programs, including resumption of pivotal Phase 2 trial for Danon disease in 1H 2026 and initiation of Phase 1 trial for BAG3-DCM in mid-2026.
KRESLADI™ for severe LAD-I remains on track for March 28, 2026 PDUFA date, with potential for a Rare Pediatric Disease Priority Review Voucher.
Organizational realignment led to disciplined resource allocation and reduced operating expenses.
Financial highlights
Cash, cash equivalents, and investments totaled $188.9M as of December 31, 2025, providing operational runway into Q2 2027.
Research and development expenses decreased to $142.0M for 2025 from $171.2M in 2024, reflecting lower manufacturing, development, and compensation costs.
General and administrative expenses fell to $86.5M in 2025 from $102.0M in 2024, mainly due to reduced commercial preparation and payroll expenses.
Net loss narrowed to $223.1M ($2.01/share) for 2025 from $258.7M ($2.73/share) in 2024.
Restructuring and related charges totaled $3.2M in 2025.
Outlook and guidance
Cash resources expected to fund operations into Q2 2027, excluding potential PRV proceeds.
Anticipates dosing additional Danon disease patients in 1H 2026 and first BAG3-DCM patient in mid-2026.
Ongoing FDA engagement for pivotal trial design in PKP2-ACM.
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