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Savara (SVRA) investor relations material
Savara Evercore ISI 8th Annual HealthCONx Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Evercore ISI 8th Annual HealthCONx Conference summary4 Dec, 2025
Company overview and product focus
Focused on rare lung disease, specifically autoimmune pulmonary alveolar proteinosis (autoimmune PAP), with a single-asset inhaled biologic, Molbreevi, showing positive Phase 3 data.
BLA submission planned for this month, with MAA filings in Europe and the UK by end of Q1.
Aiming to be commercial stage by 2026, pending regulatory approvals.
Disease background and current treatment landscape
Autoimmune PAP is a rare lung disease managed primarily by whole lung lavage, a complex procedure performed at limited centers.
Procedure requires general anesthesia and is reserved for severe cases; mild to moderate patients have limited treatment options.
Diagnosis is often delayed, and a no-cost dry blood spot antibody test is being offered to speed up identification.
Pulmonologists are the primary clinicians managing these patients.
Epidemiology and patient identification
Prevalence estimates range from 6 to 26 per million, with claims data suggesting about 5,500 autoimmune PAP patients in the US.
A small registry exists, mostly adult patients, run out of Cincinnati Children's Hospital.
The true prevalence may be underestimated due to undiagnosed cases.
Strategy to identify undiagnosed aPAP patients?
What drives 100% OLE enrollment?
What supports Molbrivi's pricing power?
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Next Savara earnings date
Q4 20256 Mar, 2026
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Frequently asked questions
Savara Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for rare respiratory diseases. The company's main focus is on advancing its lead product candidate, molgramostim, an inhaled granulocyte-macrophage colony-stimulating factor (GM-CSF) for the treatment of autoimmune pulmonary alveolar proteinosis (aPAP). In addition to molgramostim, Savara is also developing AeroVanc, an inhaled vancomycin aimed at treating methicillin-resistant Staphylococcus aureus (MRSA) lung infections in cystic fibrosis patients. Savara is headquartered in Austin, Texas, and its shares are listed on the NASDAQ.
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