SeaStar Medical Holding (ICU) investor relations material

Executive summary

• Special Meeting scheduled for December 18, 2025, to be held virtually, with all stockholders encouraged to vote electronically or by mail.

• Record date for voting is November 3, 2025, with 35,865,834 shares of common stock outstanding and entitled to vote.

• Board recommends voting FOR all three proposals: reverse stock split, reduction of authorized shares, and adjournment if necessary.

Voting matters and shareholder proposals

• Proposal 1: Approve a 1-for-10 reverse stock split, with the Board authorized to implement within one year, without reducing authorized shares.

• Proposal 2: Approve amendment to reduce authorized common shares by 25,000,000 to 425,000,000.

• Proposal 3: Approve adjournment of the meeting if more time is needed to solicit votes for the above proposals.

• All proposals require a majority of votes cast to pass; abstentions and broker non-votes have no effect.

• Board unanimously recommends voting FOR all proposals.

Board of directors and corporate governance

• Board and executive officers are soliciting proxies and may do so by various means; no additional compensation for solicitation.

• Proxy solicitation services provided by Medicant Communications for a fee of $6,500 plus expenses.

• Security ownership table discloses beneficial ownership of directors, officers, and 5% holders as of October 28, 2025.