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Sirnaomics (2257) investor relations material
Sirnaomics H1 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H1 2025 earnings summary29 Aug, 2025
Executive summary
Clinical-stage biopharma focused on siRNA therapeutics, leveraging proprietary delivery platforms for a diversified pipeline in oncology, fibrotic diseases, aesthetics, and metabolic disorders.
Lead candidate STP705 prioritized for isSCC, advancing to pivotal phase IIb/III trials; STP707 and STP122G progressing in clinical development.
Strategic restructuring, leadership changes, and cost optimization implemented to enhance operational efficiency, extend financial runway, and prioritize high-value programs.
No revenue generated; focus remains on R&D and pipeline advancement.
Financial highlights
Net loss for the six months ended June 30, 2025 was US$3.4 million, a significant decrease from US$43.5 million year-over-year, mainly due to reduced R&D and administrative expenses.
Administrative expenses decreased 75% to US$2.6 million; R&D expenses down 79% to US$3.0 million.
Cash and cash equivalents at June 30, 2025 were US$6.9 million, down from US$11.8 million at year-end 2024.
No product sales revenue; other income decreased 87% to US$0.1 million.
Positive swing in other gains and losses, mainly from lease modification and asset disposals.
Outlook and guidance
NDA submission for STP705 targeted as early as 2027, contingent on positive clinical data and regulatory approval.
Focus on advancing clinical programs, expanding pipeline, and maintaining financial discipline.
Exploring additional financing, divestment of non-core assets, and strategic partnerships to extend financial runway.
Continued emphasis on operational agility, cost optimization, and business development to drive sustainable growth.
STP705: Rationale for isSCC prioritization
Detail key cost savings from restructuring efforts
RNAimmune: Update on external financing strategy
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Next Sirnaomics earnings date
H2 202526 Mar, 2026
Next Sirnaomics earnings date
H2 202526 Mar, 2026
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Frequently asked questions
Sirnaomics Ltd is a biopharmaceutical company focused on the discovery, development, and commercialization of RNA interference (RNAi) therapeutics. The company specializes in developing RNA-based drugs for the treatment of diseases in areas such as oncology, fibrosis, and other serious conditions. Its platform integrates proprietary delivery technologies designed to enhance the targeting and effectiveness of RNAi-based treatments. Sirnaomics Ltd conducts research, clinical development, and regulatory activities as part of its product advancement strategy. The company is headquartered in Suzhou, China, and its shares are listed on the HKEX.
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