Solid Biosciences
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Solid Biosciences (SLDB) investor relations material

Solid Biosciences Q3 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2026 earnings summary4 Nov, 2026

Executive summary

  • SGT-003 Phase 1/2 and Phase 3 trials advanced; 53 INSPIRE DUCHENNE participants had received treatment, and an FDA meeting on preliminary data and a potential accelerated-approval pathway was scheduled for late Q4 2026.

  • No commercial product revenue to date; losses are expected to continue, with September 30 liquidity projected to fund operations into H1 2028.

Financial highlights

  • Q3 2026 operating expenses were $57.7M, up 20.0% YoY; net loss was $53.9M versus $45.8M, and loss per share was $0.36 versus $0.48.

  • 9M 2026 operating expenses were $172.3M, up 32.8% YoY; net loss was $165.5M versus $124.5M, and loss per share was $1.23 versus $1.46.

  • Cash, cash equivalents and available-for-sale securities totaled $348.9M at September 30, 2026, excluding $1.3M restricted cash; no debt was outstanding.

  • Q3 R&D was $43.6M versus $38.9M and G&A was $14.1M versus $9.2M; increases reflected personnel and SGT-003/SGT-212 manufacturing and clinical or research costs.

Outlook and guidance

  • Cash and available-for-sale securities were expected to fund operating expenses and capital needs into H1 2028; additional funding will be needed to continue beyond then.

  • R&D and G&A expenses are expected to rise as trials enroll and advance, manufacturing scales, and pipeline and commercial-readiness work continues.

  • SGT-212 initial data were anticipated in Q1 2027, subject to enrollment; SGT-501 first dosing was anticipated by year-end 2026, with initial safety data in H1 2027, subject to enrollment.

  • FDA meeting minutes will inform a subsequent update on SGT-003 regulatory discussions.

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Jefferies Global Healthcare Conference16 Nov, 2026
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Jefferies Global Healthcare Conference16 Nov, 2026

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Frequently asked questions

Solid Biosciences Inc. is a life science company dedicated to developing therapies for neuromuscular and cardiac diseases. The company's primary focus includes advancing a portfolio of gene therapy candidates for various conditions, such as Duchenne muscular dystrophy with its lead product candidate SGT-003, Friedreich's ataxia treated by AVB-202-TT, and BAG3-mediated dilated cardiomyopathy with AVB-401. Solid Biosciences is also working on developing platform technologies that include dual gene expression, allowing for the packaging of multiple transgenes into one vector, and the exploration of novel capsids. The company's mission is driven by a commitment to improve the daily lives of patients living with these debilitating diseases, supported by collaborations and partnerships, including a notable agreement with Ultragenyx Pharmaceutical Inc. for the development and commercialization of new gene therapies for Duchenne muscular dystrophy. The company is headquartered in Charlestown, Massachusetts, and its shares are listed on the Nasdaq.