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SynAct Pharma (SYNACT) investor relations material
SynAct Pharma Q2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q2 2025 earnings summary20 Aug, 2025
Executive summary
Focused on advancing resomelagon (AP1189) for inflammatory and autoimmune diseases, especially rheumatoid arthritis (RA), and host-directed therapy in viral infections, with a clear two-track development strategy.
ADVANCE Phase 2b study in newly diagnosed severe RA is on track, aiming to complete enrollment by end of 2025 and report key data in Q1 2026.
Initiated a Phase 2 study in Dengue and planning a Phase 2 study in Polymyalgia Rheumatica (PMR) in H2 2025.
Strengthened financial position through a SEK 37 million share issue, SEK 30 million credit facility, and warrant conversions, extending runway into 2027.
Financial highlights
Net sales were SEK 0 for both Q2 and H1 2025, consistent with prior periods.
Q2 operating expenses increased 58% year-over-year to SEK 30,345 thousand; H1 operating expenses rose 30% to SEK 58,443 thousand.
Q2 loss after tax was SEK 27,522 thousand (vs. SEK 18,628 thousand in Q2 2024); H1 loss after tax was SEK 52,207 thousand (vs. SEK 43,534 thousand in H1 2024).
Q2 EPS was -0.56 SEK (vs. -0.47 SEK); H1 EPS was -1.07 SEK (vs. -1.16 SEK).
Cash and cash equivalents at June 30, 2025, were SEK 68,890 thousand (vs. SEK 62,799 thousand a year earlier).
Outlook and guidance
No revenue expected until at least 2026, post-Phase 2 program completion.
Current cash and recent financings are sufficient to fund operations for at least the next 12 months, with runway extended into 2027.
ADVANCE study enrollment to complete by end of 2025; key data expected Q1 2026.
IMN study: future resource allocation?
Funding sources for 2027 runway extension
R&D project prioritization with new funding?
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Next SynAct Pharma earnings date
Q3 202530 Oct, 2025
Next SynAct Pharma earnings date
Q3 202530 Oct, 2025
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Frequently asked questions
SynAct Pharma AB, develops medicines for acute deterioration in inflammatory diseases. The company's lead product, Synacto®, is a mix of three anti-inflammatory protease inhibitors for the treatment of patients who have recently had a heart attack, have re-opened their old heart wounds due to surgery, or are going to undergo procedures in which blood clotting is needed. SynAct Pharma AB is based in Lund, Sweden.
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