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SynAct Pharma (SYNACT) investor relations material
SynAct Pharma Life Science Summit 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Life Science Summit 2025 summary17 Nov, 2025
Strategic focus and development programs
Advancing a dual development strategy for resomelagon (AP1189) in newly diagnosed rheumatoid arthritis and as host-directed therapy for severe viral infections.
Phase IIB trial in rheumatoid arthritis targets newly diagnosed patients with high disease activity and poor prognosis factors.
Host-directed therapy program addresses hyper-inflammatory responses in viral infections, with ongoing studies in respiratory insufficiency and dengue.
Pipeline includes additional peptide-based projects and plans for business development partnerships for phase III advancement.
Clinical progress and upcoming milestones
Over 80% of patients recruited for the 240-patient phase IIB rheumatoid arthritis study, with key results expected in the first half of next year.
Clinical studies in viral infections, including COVID and dengue, are ongoing, with a dengue study set to begin in Brazil during the next epidemic season.
Major data readouts and business development activities are anticipated in 2025, with continued updates on respiratory insufficiency studies.
Funding is secured through 2027, supporting ongoing and planned clinical programs.
Scientific approach and competitive landscape
Resomelagon is a first-in-class, non-suppressive therapy that modulates immune response by shifting macrophage phenotype to promote inflammation resolution.
Therapy aims to reduce reliance on glucocorticoids and postpone second-line treatments, potentially improving patient outcomes.
Resolution therapy is positioned as a novel, patient-friendly oral treatment, with limited direct competition and growing industry recognition.
Resomelagon's impact on RA treatment paradigm
Prioritized viral infection targets for AP1189
Phase 3 partnership strategy for resomelagon
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Next SynAct Pharma earnings date
Q4 202518 Feb, 2026
Next SynAct Pharma earnings date
Q4 202518 Feb, 2026
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SynAct Pharma AB, develops medicines for acute deterioration in inflammatory diseases. The company's lead product, Synacto®, is a mix of three anti-inflammatory protease inhibitors for the treatment of patients who have recently had a heart attack, have re-opened their old heart wounds due to surgery, or are going to undergo procedures in which blood clotting is needed. SynAct Pharma AB is based in Lund, Sweden.
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