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Syndax Pharmaceuticals (SNDX) investor relations material

Syndax Pharmaceuticals H.C. Wainwright 27th Annual Global Investment Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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H.C. Wainwright 27th Annual Global Investment Conference summary8 Sep, 2025

Conference overview

  • Over 600 companies presented at the HC Wainwright 27th Annual Global Investment Conference, with a focus on innovative therapies and investment opportunities.

  • Syndax Pharmaceuticals presented updates on its commercial-stage cancer therapies and future growth plans.

Product performance and financial highlights

  • Achieved $100 million in net sales in the first six months, exceeding expectations and supporting a path to profitability.

  • Maintains over $500 million in cash with a stabilizing expense base, enabling investment in product franchises.

  • Revuforj and Nivtemo are both contributing significantly to cash flow and business momentum.

Revuforj: Market position and growth

  • First and only FDA-approved menin inhibitor for relapsed/refractory acute leukemia with KMT2A translocation, approved in late 2024.

  • Demonstrated 43% quarter-over-quarter sales growth, with over 1,300 prescriptions and 500+ patients treated.

  • Secured first-mover advantage, broad label, and inclusion in NCCN guidelines for AML and ALL.

  • Anticipates approval for relapsed/refractory NPM1 in October, expanding the addressable market to 6,500 patients and $5 billion.

  • Ongoing trials aim to expand into frontline settings for both fit and unfit patient populations.

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Frequently asked questions

Syndax Pharmaceuticals Inc. is a biopharmaceutical company focused on developing therapies for cancer. The company's lead programs target immune pathways and tumor microenvironments to enhance the body’s ability to fight cancer. Syndax's pipeline includes treatments for both solid tumors and hematologic cancers, aiming to address unmet medical needs by improving outcomes for cancer patients through novel combination therapies. The company is headquartered in Waltham, Massachusetts, and its shares are listed on the NASDAQ.

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