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Syndax Pharmaceuticals
Syndax Pharmaceuticals (SNDX) investor relations material
Syndax Pharmaceuticals TD Cowen 46th Annual Health Care Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.TD Cowen 46th Annual Health Care Conference summary2 Mar, 2026
Company overview and recent performance
Two commercial products in hematology: one for acute AML, another for chronic GVHD, with three approvals in about a year.
Achieved record first-year sales for AML product, with $44M in Q4 and $125M for the full year, and high formulary coverage.
Organization is well-scaled and financially positioned to reach profitability in the near term, with cash reserves to support operations.
Product launches and growth drivers
Revuforj's launch driven by KMT2A and NPM1 indications, with about 50% market penetration in KMT2A and growing NPM1 share post-approval.
Post-transplant maintenance is a significant growth driver, with 40%-45% of transplant patients returning to therapy.
Duration of therapy expected to increase from 4-6 months in year one to 6-12 months in year two, supporting revenue growth.
Market opportunity and financial outlook
Total addressable market for relapsed/refractory AML estimated at over $2B, with $750M for KMT2A and $1.2B-$1.4B for NPM1.
Frontline opportunity could reach $10B for both products combined, with longer therapy durations.
Niktimvo in chronic GVHD has a third-line+ market of 6,500 patients and a potential $2B+ opportunity, expanding to $5B+ in frontline.
What drives Revuforj R/R market size disconnect?
What supports Niktimvo's IPF mechanism of action?
How will Revuforj be first to frontline AML data?
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Next Syndax Pharmaceuticals earnings date
Leerink Global Healthcare Conference 202611 Mar, 2026
Syndax Pharmaceuticals
Next Syndax Pharmaceuticals earnings date
Leerink Global Healthcare Conference 202611 Mar, 2026
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Frequently asked questions
Syndax Pharmaceuticals Inc. is a biopharmaceutical company focused on developing therapies for cancer. The company's lead programs target immune pathways and tumor microenvironments to enhance the body’s ability to fight cancer. Syndax's pipeline includes treatments for both solid tumors and hematologic cancers, aiming to address unmet medical needs by improving outcomes for cancer patients through novel combination therapies. The company is headquartered in Waltham, Massachusetts, and its shares are listed on the NASDAQ.
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