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Tyra Biosciences (TYRA) investor relations material
Tyra Biosciences H.C. Wainwright 27th Annual Global Investment Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H.C. Wainwright 27th Annual Global Investment Conference summary10 Sep, 2025
Company overview and scientific focus
Precision medicine company focused on FGFR biology, with all clinical compounds developed in-house using the SNAP chemistry platform.
Lead asset is a first-in-class, highly selective FGFR3 inhibitor, targeting significant unmet needs in bladder cancer and growth disorders.
Oral FGFR3 inhibitor is in phase 2 trials for both non-muscle invasive bladder cancer (NMIBC) and achondroplasia (ACH), with differentiated selectivity and safety profile.
Clinical development and strategy
Phase 2 studies in NMIBC and ACH are running in parallel, with dedicated teams and equal resource allocation.
In NMIBC, the goal is to match or exceed current complete response (CR) rates while offering a less invasive, oral alternative to surgery and intravesical therapies.
In ACH, the aim is to restore growth velocity closer to typical levels, surpassing the efficacy ceiling of current therapies by achieving higher FGFR3 target engagement.
Differentiation and competitive landscape
Oral administration offers a significant advantage over device-based or injectable therapies, reducing patient burden and improving convenience.
FGFR3 selectivity avoids toxicities associated with pan-FGFR inhibitors, such as hyperphosphatemia and FGFR2-driven side effects, making chronic use in children feasible.
UroGPO and specialty pharmacy partnerships enable urologists to prescribe oral drugs without financial disadvantage, supporting adoption in community practice.
Oral NMIBC: How to shift urologist incentives?
Achondroplasia: How to exceed 6 cm growth rate?
Dual market potential: What drives long-term value?
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Next Tyra Biosciences earnings date
Q3 202514 Nov, 2025
Next Tyra Biosciences earnings date
Q3 202514 Nov, 2025
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Frequently asked questions
Tyra Biosciences Inc. is a clinical-stage biotechnology company specializing in the development of precision medicines targeted at Fibroblast Growth Factor Receptor biology. Leveraging its proprietary platform, Tyra Biosciences focuses on creating drugs through iterative molecular snapshots which aid in predicting genetic alterations and developing therapies for oncology and genetically defined conditions. The company is headquartered in Carlsbad, California, and its shares are listed on the NASDAQ.
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