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Vaxart (VXRT) investor relations material

Vaxart Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary13 Nov, 2025

Executive summary

  • Entered an exclusive worldwide license and collaboration agreement with Dynavax for the oral COVID-19 vaccine, including a $25 million upfront payment, $5 million equity investment, and potential proceeds up to $700 million in license, regulatory, and milestone fees plus royalties, extending cash runway into Q2 2027.

  • COVID-19 Phase 2b trial funding from BARDA was reduced after a stop work order, with enrollment cut from 10,000 to 5,400 participants; future funding is under review.

  • Positive Phase 1 results for the second-generation norovirus vaccine candidate, showing significantly stronger antibody responses; next steps depend on partnership or funding.

  • Multiple data readouts for the COVID-19 Phase 2b trial are expected in 2026, with sentinel cohort data in Q1 and full cohort data in Q4.

  • Delisting from Nasdaq in September 2025 due to noncompliance with minimum bid price; now trading on OTCQX.

Financial highlights

  • Q3 2025 revenue was $72.4 million, up sharply year-over-year, primarily due to BARDA contract revenue.

  • Operating expenses for Q3 2025 were $80.2 million, up 313% year-over-year, mainly due to increased COVID-19 clinical trial costs.

  • Net loss for Q3 2025 was $8.1 million, improved from $14.1 million in Q3 2024; net loss per share was $0.04.

  • Cash, cash equivalents, and investments totaled $28.8 million as of September 30, 2025; cash runway extended into Q2 2027.

  • Nine-month revenue was $133.0 million, up 884% year-over-year.

Outlook and guidance

  • On track to report 12-month top-line data from the COVID-19 Phase 2b Sentinel cohort in Q1 2026 and full cohort in Q4 2026.

  • Next clinical trial for the norovirus program anticipated to start in 2026, pending funding or partnership.

  • Aggressively pursuing additional strategic partnerships and non-dilutive funding to extend cash runway and achieve milestones.

  • Future funding for the COVID-19 program is uncertain due to BARDA contract modifications and reduced trial enrollment.

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Frequently asked questions

Vaxart Inc. is a biotechnology company focused on developing oral vaccines that are administered using tablet formulations rather than injections. The company's proprietary oral vaccine platform is designed to stimulate immune responses in mucosal tissues, which are the first line of defense against many infections. Vaxart's vaccine candidates target a range of infectious diseases, including influenza, norovirus, and COVID-19. The company is headquartered in South San Francisco, California, and its shares are listed on the NASDAQ.

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