Vaxart
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Vaxart (VXRT) investor relations material

Vaxart Global BioInnovation Forum 2026 summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Global BioInnovation Forum 2026 summary13 Jan, 2026

Innovation in vaccine delivery

  • Focus on oral recombinant pill vaccines to replace traditional injections, aiming for greater convenience and accessibility.

  • Technology leverages mucosal immunology to induce IgA antibodies at pathogen entry points, enhancing cross-protection.

  • Platform allows rapid adaptation to new pathogens by inserting genes of interest into a stable adenoviral vector.

  • Tablets are thermostable, easy to distribute, and eliminate the need for cold chain logistics and medical waste.

  • Oral vaccines can be self-administered, increasing global access and potentially improving vaccination rates.

Clinical and preclinical data highlights

  • Preclinical studies in animal models demonstrated reduced transmission and cross-protection against multiple strains.

  • Norovirus challenge studies showed prevention of infection and robust immune responses in diverse populations, including lactating mothers and the elderly.

  • COVID-19 oral vaccine produced strong mucosal and T-cell responses in phase 1 trials.

  • Influenza oral vaccine reduced symptomatic infection more than a leading injected vaccine in head-to-head studies.

  • Safety profile across nearly 1,200 subjects is comparable to placebo, with no injection site reactions.

Forward-looking statements and upcoming milestones

  • Top-line results from a 400-person COVID-19 trial comparing oral and mRNA vaccines expected in Q1 2026.

  • Larger 5,000-subject COVID-19 trial results anticipated in late 2026.

  • Phase 2b norovirus vaccine study could begin as early as 2026, following strong head-to-head data.

  • Ongoing development of seasonal and avian influenza programs, leveraging rapid platform adaptability.

  • Emphasis on the potential for the oral platform to revolutionize vaccine distribution and acceptance.

How does mucosal immunity enhance vaccine protection?
What are the expected COVID-19 trial results in 2026?
How do oral vaccines improve global health access?
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Q4 202519 Mar, 2026
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Frequently asked questions

Vaxart Inc. is a biotechnology company focused on developing oral vaccines that are administered using tablet formulations rather than injections. The company's proprietary oral vaccine platform is designed to stimulate immune responses in mucosal tissues, which are the first line of defense against many infections. Vaxart's vaccine candidates target a range of infectious diseases, including influenza, norovirus, and COVID-19. The company is headquartered in South San Francisco, California, and its shares are listed on the NASDAQ.

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