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Vericel (VCEL) investor relations material

Vericel Stephens Annual Investment Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Stephens Annual Investment Conference summary20 Nov, 2025

Financial and operational highlights

  • Achieved record Q3 revenue of $67.5 million, with MACI contributing $56 million and 25% growth; burn care also had a strong quarter at $12 million.

  • Adjusted EBITDA grew 70% to $17 million with a 25% margin; GAAP net income was $5 million; generated $20 million in operating/free cash flow.

  • Salesforce expansion is nearly complete, increasing from 75 to 100 territories, with new reps expected to be fully operational by January 1.

  • Margin expansion has outpaced expectations, with gross margin guided at 74% and adjusted EBITDA margin at 26% for the year.

  • Over $180 million in cash and strong free cash flow position support ongoing investments and disciplined M&A opportunities.

MACI growth drivers and market penetration

  • MACI's total addressable market (TAM) is about 60,000 patients annually, with strong penetration in patella and large defects, and single-digit penetration in smaller defects.

  • Arthroscopic delivery (Arthro) is expanding MACI's reach, especially for smaller defects and the trochlear area, with rapid adoption among trained surgeons.

  • Surgeon training has led to higher biopsy and implant growth, with new surgeons quickly adopting MACI after Arthro training.

  • Early data shows higher conversion rates for MACI Arthro implanting surgeons, with implant growth outpacing biopsy growth.

  • Salesforce expansion aims to drive both new surgeon activation and deeper penetration in existing accounts, supporting long-term growth targets.

Pricing, guidance, and long-term outlook

  • Maintains confidence in mid to high single-digit annual price increases for MACI, supported by strong prior authorization rates and product positioning as a high-tech biologic.

  • Preliminary outlook for MACI is 20% growth for next year, with expectations for continued momentum as more surgeons are trained and Salesforce expansion matures.

  • Long-term initiatives, including international expansion and process improvements, are expected to drive growth toward a $500 million MACI business and $200 million adjusted EBITDA by decade's end.

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Frequently asked questions

Vericel Corporation is a biopharmaceutical company focused on developing and manufacturing advanced cell therapies for patients with severe diseases and injuries. The company’s products include autologous cell therapies used in the treatment of cartilage defects, burns, and other medical conditions. The company is headquartered in Cambridge, Massachusetts, and its shares are listed on the NASDAQ.

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