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Viking Therapeutics
Viking Therapeutics (VKTX) investor relations material
Viking Therapeutics Corporate presentation summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Corporate presentation summary14 Jan, 2026
Strategic focus and pipeline
Focused on developing novel therapeutics for metabolic and endocrine diseases, with multiple clinical programs showing strong efficacy data.
Lead asset VK2735, a GLP-1/GIP dual agonist, is being developed in both injectable and oral forms for obesity, with Phase 3 and Phase 2 studies underway or completed.
Additional programs include an amylin agonist for obesity (IND planned 1Q26), VK2809 for MASH (successful Phase 2b), and VK0214 for X-ALD (successful Phase 1b).
VK2735 clinical results and efficacy
VK2735 demonstrated up to 14.7% mean weight loss after 13 weeks in Phase 2 subcutaneous studies, with dose-dependent effects and no plateau observed.
Oral VK2735 achieved up to 12.2% mean weight loss after 13 weeks, with progressive and durable effects maintained post-dosing.
Both formulations showed rapid, progressive weight loss, with significant differences from placebo at all time points for doses above 15 mg.
Exploratory maintenance cohorts suggest lower maintenance doses can sustain or extend weight loss.
Safety and tolerability
Majority of treatment-emergent adverse events (TEAEs) were mild to moderate, with GI-related events (nausea, vomiting, diarrhea, constipation) most common and generally subsiding over time.
Discontinuation rates were dose-dependent and mainly related to GI side effects, but most events resolved with titration.
Promising tolerability profile observed through high dose levels in both oral and injectable studies.
How does VK2735 PK profile compare to tirzepatide?
What is the expected timeline for oral maintenance data?
Assess the financial runway based on current burn rate.
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Next Viking Therapeutics earnings date
Q4 20254 Feb, 2026
Viking Therapeutics
Next Viking Therapeutics earnings date
Q4 20254 Feb, 2026
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Frequently asked questions
Viking Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing innovative therapies for metabolic and endocrine disorders. The company utilizes small-molecule drug technology to target conditions such as liver diseases, muscle disorders, and other chronic illnesses. The company is headquartered in San Diego, California, and its shares are listed on the NASDAQ.
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