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Viking Therapeutics (VKTX) investor relations material
Viking Therapeutics Corporate Presentation summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Corporate Presentation summary19 Nov, 2025
Strategic focus and pipeline
Advancing novel therapeutics for metabolic and endocrine diseases, with multiple programs showing strong efficacy data.
Lead asset VK2735, a dual GLP-1/GIP agonist, is in Phase 3 for obesity, with both injectable and oral formulations.
Oral VK2735 achieved primary endpoints in Phase 2, showing significant weight loss and promising tolerability.
Additional assets include VK2809 for MASH (Phase 2b complete) and VK0214 for X-ALD (Phase 1b complete).
Amylin agonist for obesity is planned to enter IND in 1Q26.
VK2735 clinical results and safety
Oral VK2735 led to up to 12.2% mean weight loss after 13 weeks, with effects maintained post-dosing.
Subcutaneous VK2735 showed up to 14.7% mean weight loss in Phase 2, with durable results and potential for monthly dosing.
Majority of adverse events were mild to moderate, mainly GI-related, and typically resolved over time.
Exploratory cohorts suggest lower maintenance doses can sustain or extend weight loss.
Discontinuation rates and TEAEs were dose-dependent, with nausea, vomiting, and constipation most common.
Ongoing and future studies
Two Phase 3 studies (VANQUISH 1 and 2) are underway for VK2735 in obesity and type 2 diabetes; VANQUISH 1 enrollment is complete.
Maintenance study is evaluating transition to monthly subcutaneous or oral dosing, with results expected in 2026.
End of Phase 2 meeting with FDA is scheduled for later in the year.
Oral VK2735 FDA meeting outcome impact
Amylin agonist IND: What's the market view?
VK2735 maintenance study: key implications
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Next Viking Therapeutics earnings date
Q4 20254 Feb, 2026
Next Viking Therapeutics earnings date
Q4 20254 Feb, 2026
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Frequently asked questions
Viking Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing innovative therapies for metabolic and endocrine disorders. The company utilizes small-molecule drug technology to target conditions such as liver diseases, muscle disorders, and other chronic illnesses. The company is headquartered in San Diego, California, and its shares are listed on the NASDAQ.
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